Title:
MODIFIED NUCLEOSIDE OR NUCLEOTIDE
Document Type and Number:
WIPO Patent Application WO/2022/083686
Kind Code:
A1
Abstract:
A modified nucleoside or nucleotide, the 3'-OH of the modified nucleoside or nucleotide being reversibly blocked; meanwhile, the present invention also relates to a kit comprising the nucleoside or nucleotide, and a sequencing method based on the nucleoside or nucleotide.
Inventors:
XU XUN (CN)
TENG BO (CN)
ZHANG WENWEI (CN)
CHEN AO (CN)
LI HANDONG (CN)
YAN SHENGYI (CN)
ZHUO SHITIAN (CN)
SHEN LIANG (CN)
ZHANG YONGHUI (CN)
GAO NANFENG (CN)
ZHAO JIE (CN)
LIAO SHA (CN)
TENG BO (CN)
ZHANG WENWEI (CN)
CHEN AO (CN)
LI HANDONG (CN)
YAN SHENGYI (CN)
ZHUO SHITIAN (CN)
SHEN LIANG (CN)
ZHANG YONGHUI (CN)
GAO NANFENG (CN)
ZHAO JIE (CN)
LIAO SHA (CN)
Application Number:
PCT/CN2021/125262
Publication Date:
April 28, 2022
Filing Date:
October 21, 2021
Export Citation:
Assignee:
BGI SHENZHEN (CN)
BGI SHENZHEN CO LTD (CN)
BGI SHENZHEN CO LTD (CN)
International Classes:
C07H19/10; C12Q1/68
Domestic Patent References:
| WO2019071474A1 | 2019-04-18 | |||
| WO2018107350A1 | 2018-06-21 | |||
| WO2008037568A2 | 2008-04-03 | |||
| WO2014139596A1 | 2014-09-18 | |||
| WO2018129214A1 | 2018-07-12 |
Foreign References:
| US20160010150A1 | 2016-01-14 |
Other References:
SHOSHANI ILANA, QIU HOWARD, JOHNSON FRANCIS, JOHNSON ROGER A.: "Synthesis of Iodo-aryl-azido Adenosine Analogs as Affinity Ligands for Adenylyl Cyclase", NUCLEOSIDES AND NUCLEOTIDES, vol. 13, no. 9, 1 September 1994 (1994-09-01), US , pages 1977 - 1989, XP009535854, ISSN: 0732-8311, DOI: 10.1080/15257779408010676
J. SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
F.M. AUSUBEL ET AL.: "Short Protocols in Molecular Biology", 1995, JOHN WILEY&SONS
CHEM. EUR. J., vol. 5, no. 3, 1999, pages 951 - 960
ZHU ET AL., CYTOMETRY, vol. 28, 1997, pages 206 - 211
PROBER, SCIENCE, vol. 238, 1987, pages 336 - 341
CONNELL ET AL., BIOTECHNIQUES, vol. 5, no. 4, 1987, pages 342 - 384
ANSORGE ET AL., NUCL. ACIDS RES., vol. 15, no. 11, 1987, pages 4593 - 4602
SMITH ET AL., NATURE, vol. 321, 1986, pages 674
TET. LET., vol. 46, 2000, pages 8867 - 8871
J. AM. CHEM. SOC., vol. 123, 2001, pages 8101 - 8108
EMPODOCLES ET AL., NATURE, vol. 399, 1999, pages 126 - 130
REICHERT ET AL., ANAL. CHEM., vol. 72, 2000, pages 6025 - 6029
LACOSTE, PROC. NATL. ACAD. SCI USA, vol. 97, no. 17, 2000, pages 9461 - 9466
GUILLIER ET AL., CHEM. REV., vol. 100, 2000, pages 2092 - 2157
LEE ET AL., J. ORG. CHEM., vol. 64, 1999, pages 3454 - 3460
BURGESS ET AL., J. ORG. CHEM., vol. 62, 1997, pages 5165 - 5168
J. SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
F.M. AUSUBEL ET AL.: "Short Protocols in Molecular Biology", 1995, JOHN WILEY&SONS
CHEM. EUR. J., vol. 5, no. 3, 1999, pages 951 - 960
ZHU ET AL., CYTOMETRY, vol. 28, 1997, pages 206 - 211
PROBER, SCIENCE, vol. 238, 1987, pages 336 - 341
CONNELL ET AL., BIOTECHNIQUES, vol. 5, no. 4, 1987, pages 342 - 384
ANSORGE ET AL., NUCL. ACIDS RES., vol. 15, no. 11, 1987, pages 4593 - 4602
SMITH ET AL., NATURE, vol. 321, 1986, pages 674
TET. LET., vol. 46, 2000, pages 8867 - 8871
J. AM. CHEM. SOC., vol. 123, 2001, pages 8101 - 8108
EMPODOCLES ET AL., NATURE, vol. 399, 1999, pages 126 - 130
REICHERT ET AL., ANAL. CHEM., vol. 72, 2000, pages 6025 - 6029
LACOSTE, PROC. NATL. ACAD. SCI USA, vol. 97, no. 17, 2000, pages 9461 - 9466
GUILLIER ET AL., CHEM. REV., vol. 100, 2000, pages 2092 - 2157
LEE ET AL., J. ORG. CHEM., vol. 64, 1999, pages 3454 - 3460
BURGESS ET AL., J. ORG. CHEM., vol. 62, 1997, pages 5165 - 5168
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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