MODIFIED RELEASE DOSAGE FORMS

Title:

MODIFIED RELEASE DOSAGE FORMS

Document Type and Number:

WIPO Patent Application WO2003026629

Kind Code:

A3

Abstract:

A dosage form comprises: (a) at least one active ingredient: (b) a core having a first surface portion upon which resides a first coating and a second surface portion which is substantially free of the first coating; and (c) a shell which resides upon at least a portion of the second surface portion, wherein the shell comprises a different material from the first coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b)a core comprising a center portion having an exterior surface and an annular portion having an exterior surface and an interior surface, wherein the annular portion interior surface is in contact with at least a portion of the center portion exterior surface, and a coating resides on at least a portion of the annular portion exterior surface; and (c) a shell which resides upon at least a portion of the exterior surface of the center portion, wherein the shell comprises a different material than the impermeable coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b) a core having an outer surface and a cavity which extends at least partially through the core such that the core outer surface has at least a first opening therein; (c) a first coating which resides on at least a portion of the core outer surface, wherein the first shell portion comprises a different material from the first coating; and (d) a first shell portion which is adjacent to the first opening and covers at least the first opening.

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Inventors:

LEE DER-YANG (US)
LI SHUN-POR (US)
SOWDEN HARRY S (US)
THOMAS MARTIN (US)
WYNN DAVID (US)

Application Number:

PCT/US2002/031117

Publication Date:

March 04, 2004

Filing Date:

September 28, 2002

Export Citation:

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Assignee:

MCNEIL PPC INC (US)
LEE DER-YANG (US)
LI SHUN-POR (US)
SOWDEN HARRY S (US)
THOMAS MARTIN (US)
WYNN DAVID (US)

International Classes:

A23G1/00; A23G3/34; A23G1/54; A23G3/00; A23G3/04; A23G3/36; A23G3/54; A23L1/00; A23L1/09; A23L1/30; A61J3/00; A61J3/06; A61J3/10; A61K9/00; A61K9/14; A61K9/20; A61K9/22; A61K9/24; A61K9/26; A61K9/28; A61K9/30; A61K9/32; A61K9/34; A61K9/36; A61K9/38; A61K9/48; A61K31/136; A61K31/137; A61K31/277; A61K47/10; A61K47/14; A61K47/26; A61K47/30; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/44; A61K47/46; A61P11/00; B30B11/08; B30B11/34; B30B15/30; G06F17/30; A61K9/50; (IPC1-7): A61K9/28

Foreign References:

US3146169A	1964-08-25
US5681584A	1997-10-28
GB1372040A	1974-10-30
EP0861659A1	1998-09-02

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