Title:
MONOOXYGENASE MUTANT, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/153183
Kind Code:
A1
Abstract:
The present invention relates to the technical field of genetic engineering, and provides a monooxygenase mutant, a preparation method therefor and an application thereof. The monooxygenase mutant has any one of the amino acid sequences shown in (I) and (II): (I) an amino acid sequence having at least 80% identity with the amino acid sequence shown in SEQ ID NO. 1; and (II) an amino acid sequence obtained by modifying, substituting, deleting, or adding one or several amino acids to the amino acids at 23-508 positions of the amino acid sequence shown in SEQ ID NO. 1, the substitution referring to a substitution of 1-34 amino acids, wherein the mutant has the activity of monooxygenase.
Inventors:
HONG HAO (CN)
GAGE JAMES (CN)
LU JIANGPING (CN)
JIAO XUECHENG (CN)
ZHANG NA (CN)
LI RUI (CN)
ZHANG KEJIAN (CN)
ZHANG YU (CN)
GAGE JAMES (CN)
LU JIANGPING (CN)
JIAO XUECHENG (CN)
ZHANG NA (CN)
LI RUI (CN)
ZHANG KEJIAN (CN)
ZHANG YU (CN)
Application Number:
PCT/CN2018/075811
Publication Date:
August 15, 2019
Filing Date:
February 08, 2018
Export Citation:
Assignee:
ASYMCHEM LAB TIANJIN CO LTD (CN)
International Classes:
C12N9/02; C12N15/53; C12P17/12
Foreign References:
| US20040267001A1 | 2004-12-30 | |||
| CN107384880A | 2017-11-24 | |||
| CN105695425A | 2016-06-22 | |||
| CN105695425A | 2016-06-22 | |||
| CN107384880A | 2017-11-24 |
Other References:
See also references of EP 3733841A4
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
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