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Title:
MULTI-LECTIN AFFINITY CHROMATOGRAPHY AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2005107491
Kind Code:
A3
Abstract:
Methods, compositions, and kits related to the use of multi-ligand affinity chromatography are described. The methods include those related to identification of glycoprotein panels for analyzing and diagnosisng disease.

Inventors:
HANCOCK WILLIAM S (US)
YANG ZIPING (US)
HINCAPIE MARINA (US)
Application Number:
PCT/US2005/015919
Publication Date:
December 22, 2005
Filing Date:
May 05, 2005
Export Citation:
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Assignee:
UNIV NORTHEASTERN (US)
HANCOCK WILLIAM S (US)
YANG ZIPING (US)
HINCAPIE MARINA (US)
International Classes:
A23J1/00; C07K1/22; C07K17/08; C07K17/14; G01N33/53; G01N33/68; (IPC1-7): C07K1/22; C07K17/08; C07K17/14; G01N33/53
Other References:
FREIER T ET AL: "Affinity Chromatography on Immobilized Hog Gastric Mucin and Ovomucoid. A General Method for Isolation of Lectins.", BIOL CHEM HOPPE-SEYLER., vol. 366, no. 11, November 1985 (1985-11-01), pages 1023 - 1028, XP008082928
SELA BA ET AL: "Isolation of Lectins of Different Specificities on a Single Affinity Adsorbent.", J BIOL CHEM., vol. 250, no. 18, September 1975 (1975-09-01), pages 7535 - 7538, XP002993233
YANG Z ET AL: "Approach to the Comprehensive Analysis of Glycoproteins Isolated from Human Serum Using a Multi-Lectin Affinity Column.", J OF CHROMATOGRAPHY A., vol. 1053, 2004, pages 79 - 88, XP019015976
GELTOSKY JE ET AL: "Use of Common Plant Lectins for Isolation and Characterization of Constitutive And Developmentally Regulated Cell Surface Associated Glycoproteins of Dictyostelium Discoideum.", CELL SURFACE CARBOHYDRATES AND BIOL RECOG., vol. 23, January 1978 (1978-01-01), pages 613 - 619, XP008082932
LOTAN R ET AL: "Activities of lectins and their immobilized Derivatives in Detergent Solutions. Implications on the Use of Lectin Affinity Chromatography for the Purification of Membrane Glycoproteins.", BIOCHEMISTRY., vol. 16, no. 9, May 1977 (1977-05-01), pages 1787 - 1794, XP002993234
COOK GMW ET AL: "Lectin-Mediated Isolation of Cells Surface Glycoproteins.", METHODS IN ENZYMOLOGY., vol. 184, January 1990 (1990-01-01), pages 304 - 314, XP008082929
HAYUNGA EG ET AL: "Characterization of Surface Glycoproteins on Schistosoma Mansoni Adult Worms by Lectin Affinity Chromatography.", J PARASIT., vol. 72, no. 2, April 1986 (1986-04-01), pages 283 - 291, XP008082933
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