Title:
MULTI-SPECIFIC ANTIBODY AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/238932
Kind Code:
A1
Abstract:
Provided are a multi-specific antibody or an antigen binding fragment thereof. The multi-specific antibody or the antigen binding fragment thereof can bind to two or more antigens, or two or more epitopes of the same antigen. Also provided is use of the antibody or the antigen binding fragment in treatment, diagnosis, and prognosis of inflammatory diseases, autoimmune diseases, or spinal cord injury.
Inventors:
HUANG JUNJIE (CN)
SU ZIQI (CN)
LIANG SHIZHONG (CN)
XU ZHENQIAN (CN)
LIANG BINGHUI (CN)
LI SHENGFENG (CN)
SU ZIQI (CN)
LIANG SHIZHONG (CN)
XU ZHENQIAN (CN)
LIANG BINGHUI (CN)
LI SHENGFENG (CN)
Application Number:
PCT/CN2021/095852
Publication Date:
December 02, 2021
Filing Date:
May 25, 2021
Export Citation:
Assignee:
BIO THERA SOLUTIONS LTD (CN)
International Classes:
C07K16/24; A61K39/395; A61K45/06; A61P35/00; C07K16/28; C07K16/46; C12N15/13
Foreign References:
| CN104884473A | 2015-09-02 | |||
| CN109195993A | 2019-01-11 | |||
| CN111138544A | 2020-05-12 | |||
| CN106459182A | 2017-02-22 | |||
| CN101331150A | 2008-12-24 | |||
| CN106132439A | 2016-11-16 | |||
| CN1404876A | 2003-03-26 | |||
| CN102766210A | 2012-11-07 | |||
| CN110072890A | 2019-07-30 |
Other References:
LABRIJN ARAN F.; JANMAAT MAARTEN L.; REICHERT JANICE M.; PARREN PAUL W.: "Bispecific antibodies: a mechanistic review of the pipeline", NATURE REVIEWS DRUG DISCOVERY, vol. 18, no. 8, 7 June 2019 (2019-06-07), GB , pages 585 - 608, XP036850121, ISSN: 1474-1776, DOI: 10.1038/s41573-019-0028-1
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