Title:
MULTIFUNCTIONAL FORMULATIONS AND METHODS TO CONTROL DERMATITIS AND PRURITUS
Document Type and Number:
WIPO Patent Application WO/2018/085535
Kind Code:
A3
Abstract:
This disclosure relates to multifunctional formulations, methods of manufacture and methods of use of natural topical and oral compositions to treat various dermatitis and pruritus conditions in mammals. In particular, this disclosure relates to a multifunctional topical pharmaceutical composition effective to treat dermatitis and associated pruritus comprising at least one natural plant extract TRPV1 antagonist, at least one natural plant extract is a TRPA1 antagonist, and a carrier. Also, in particular, this disclosure also relates to a mulifunctional method to treat histamine induced and non-histamine dermatitis and associated pruritus in mammals from one or more of non-atopic and atopic dermatitis (AD), contact dermatitis, allergenic contact dermatitis (ACD), psoriasis, eczema, infestations, urticarial, nociceptive, neuropathic, neurogenic, psychogenic pruritus comprising treating with a composition comprising at least one natural plant extract TRPV1 antagonist, at least one natural plant extract is a TRPA1 antagonist, and a carrier.
Inventors:
HOAG GEORGE EDWARD (US)
Application Number:
PCT/US2017/059712
Publication Date:
June 21, 2018
Filing Date:
November 02, 2017
Export Citation:
Assignee:
HOAG GEORGE EDWARD (US)
International Classes:
A61K31/045; A61K9/06; A61K31/20; A61P17/00
Domestic Patent References:
| WO2008133982A2 | 2008-11-06 |
Foreign References:
| US9415082B1 | 2016-08-16 | |||
| US20080107742A1 | 2008-05-08 | |||
| US6093745A | 2000-07-25 |
Other References:
See also references of EP 3713550A4
Attorney, Agent or Firm:
COON, Gerald L. (US)
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