MULTIVALENT NUCLEIC ACID NANOSTRUCTURE FOR NUCLEIC ACID DETECTION, AND HIGHLY SENSITIVE NUCLEIC ACID PROBE USING SAME

WIPO Patent Application WO/2020/242226

A1

The present invention relates to a nucleic acid probe system for increasing the detection efficiency of nucleic acid biomarkers, and improves the detection efficiency and detection sensitivity of biomarkers through a method for integrating a single-stranded probe sequence into a nucleic acid nanostructure. A nucleic acid nanostructure of the present invention, developed for this, converts, to a fast reaction inside the structure, some collision/reaction steps between molecules according to simple diffusion through localized aggregation of probe sequences, activates a fast signal amplification mechanism in the structure through structural flexibility so as to improve detection ability, thereby having effects of improving detection ability and effectively lowering a detection limit.

UM SOONG HO (KR)
AHN SO YEON (KR)
SHIN SEUNG WON (KR)

PCT/KR2020/006934

December 03, 2020

May 28, 2020

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PROGENEER INC (KR)

C12Q1/6876

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KR20180072480A	2018-06-29
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