Title:
MUTANT IDH1 AND IDH2 INHIBITOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/174235
Kind Code:
A1
Abstract:
Disclosed are a compound represented by formula (I) as a mutant isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) inhibitor, a preparation method therefor, and a pharmaceutical composition thereof. Also disclosed is a use of the described compound or the pharmaceutical composition thereof in the treatment of mutant IDH1 and IDH2-mediated diseases.
Inventors:
LI YABIN (CN)
XU XIAOFENG (CN)
SONG XIZHEN (CN)
DING JINGWEI (CN)
ZHANG YUNLAI (CN)
CHEN JIE (CN)
LIU XIANGYONG (CN)
DING LIEMING (CN)
WANG JIABING (CN)
XU XIAOFENG (CN)
SONG XIZHEN (CN)
DING JINGWEI (CN)
ZHANG YUNLAI (CN)
CHEN JIE (CN)
LIU XIANGYONG (CN)
DING LIEMING (CN)
WANG JIABING (CN)
Application Number:
PCT/CN2023/081225
Publication Date:
September 21, 2023
Filing Date:
March 14, 2023
Export Citation:
Assignee:
BETTA PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D251/18; A61K31/395; A61P35/00; C07D409/04
Domestic Patent References:
| WO2015003640A1 | 2015-01-15 | |||
| WO2015003360A2 | 2015-01-15 | |||
| WO2017016513A1 | 2017-02-02 |
Foreign References:
| CN104114543A | 2014-10-22 |
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