Title:
MUTANT PROMOTING HOMOLOGOUS PAIRING OF HEAVY AND LIGHT CHAINS OF MULTISPECIFIC ANTIBODY
Document Type and Number:
WIPO Patent Application WO/2024/017371
Kind Code:
A1
Abstract:
The present invention relates to a multispecific antibody, such as a bispecific antibody, comprising a mutated amino acid pair capable of promoting homologous pairing of a heavy chain and a light chain of the multispecific antibody.
Inventors:
YANG XIAO (CN)
ISSAFRAS HASSAN (CN)
GAO CHANGSHOU (CN)
WANG YI (CN)
ISSAFRAS HASSAN (CN)
GAO CHANGSHOU (CN)
WANG YI (CN)
Application Number:
PCT/CN2023/108651
Publication Date:
January 25, 2024
Filing Date:
July 21, 2023
Export Citation:
Assignee:
INNOVENT BIOLOGICS SUZHOU CO LTD (CN)
International Classes:
C07K16/18; A61K9/00; A61K39/395; A61K39/44; A61P35/00; C07K16/28; C12N1/21; C12N5/10; C12N15/13
Domestic Patent References:
| WO2021126538A1 | 2021-06-24 | |||
| WO2019196522A1 | 2019-10-17 |
Foreign References:
| US20140348839A1 | 2014-11-27 | |||
| CN113795508A | 2021-12-14 | |||
| CN114174344A | 2022-03-11 |
Attorney, Agent or Firm:
ZHONGZI LAW OFFICE (CN)
Download PDF: