MYELIN BASIC PROTEIN PEPTIDES AND USES THEREOF

Title:

MYELIN BASIC PROTEIN PEPTIDES AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO1999057241

Kind Code:

A9

Abstract:

This invention pertains generally to the treatment of autoimmune diseases of the central nervous system characterized by demyelination. In particular, this invention pertains to novel peptides derived from human myelin basic protein (MBP). When complexed with the appropriate major histocompatibility complex (MHC) molecule, these peptides can be used to treat multiple sclerosis and other demyelinating autoimmune diseases.

Inventors:

ARIMILLI SUBHASHINI (US)
DESHPANDE SHRIKANT (US)

Application Number:

PCT/US1999/009930

Publication Date:

February 17, 2000

Filing Date:

May 05, 1999

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Assignee:

CORIXA CORP (US)
ARIMILLI SUBHASHINI (US)
DESHPANDE SHRIKANT (US)

International Classes:

C12N15/09; A61K38/00; A61K39/395; A61P25/00; A61P43/00; C07K14/47; C07K16/18; C07K16/28; C07K16/40; C07K19/00; C12N5/10; C12N15/12; C12Q1/02; (IPC1-7): C12N5/08; A61K38/17; A61K39/395; C07K16/18; C07K16/28; C07K16/40; C07K19/00; C12N15/62; C12N15/85

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