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Title:
MYT1 KINASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2023/198199
Kind Code:
A1
Abstract:
Provided are a compound represented by formula (I) having an inhibitory activity against membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (MYT1 kinase), a pharmaceutically acceptable salt thereof or a pharmaceutical composition thereof, and use of the compound represented by formula (I) or a pharmaceutically acceptable salt thereof as an MYT1 kinase inhibitor in preventing or treating a disease mediated by MYT1 kinase, such as a tumor.

Inventors:
ZHU DONGXING (CN)
ZOU HAO (CN)
WANG WEIKUN (CN)
XU SHUN (CN)
LIU LANG (CN)
HUAN XIANG (CN)
ZHOU YIKE (CN)
WANG TAO (CN)
ZHU WEI (CN)
LI ZHENGTAO (CN)
Application Number:
PCT/CN2023/088447
Publication Date:
October 19, 2023
Filing Date:
April 14, 2023
Export Citation:
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Assignee:
SIMCERE ZAIMING PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D487/04; A61K31/395; A61K31/40; A61K31/407; A61K31/437; A61P35/00; C07D471/04; C07D487/14
Domestic Patent References:
WO2021195781A12021-10-07
WO2009108551A22009-09-03
WO1991018902A11991-12-12
WO2011042474A12011-04-14
Foreign References:
CN103582637A2014-02-12
CN101778850A2010-07-14
CN104768943A2015-07-08
CN110191887A2019-08-30
CN111566100A2020-08-21
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LIMITED (CN)
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