Title:
N-ACYLHYDRAZONE-DERIVATIVE-MARKER CONJUGATE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO/2021/251756
Kind Code:
A1
Abstract:
According to the present invention, a conjugate of an N-acylhydrazone derivative of chemical formula 1 and a marker, or a stereoisomer or pharmaceutically acceptable salt thereof specifically acts on cancer cells and accumulates, and is prepared on the basis of a compound having anticancer efficacy so that both treatment and diagnosis are possible and has excellent stability and solubility.
Inventors:
SOUNG NAK KYUN (KR)
KIM BO YEON (KR)
HWANG JOON SUNG (KR)
HAN HO JIN (KR)
LEE SANG KU (KR)
HAN JUN YEOL (KR)
KIM BO YEON (KR)
HWANG JOON SUNG (KR)
HAN HO JIN (KR)
LEE SANG KU (KR)
HAN JUN YEOL (KR)
Application Number:
PCT/KR2021/007223
Publication Date:
December 16, 2021
Filing Date:
June 09, 2021
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
A61K51/04; A61K49/00; A61P35/00; C07D405/12; C07D405/14
Foreign References:
| KR101790193B1 | 2017-10-25 | |||
| US20020128292A1 | 2002-09-12 | |||
| KR101565430B1 | 2015-11-03 | |||
| CN104829597A | 2015-08-12 |
Other References:
BORAEI, A. T. A. ET AL.: "Synthesis of new functionalized indoles based on ethyl indol-2-carboxylate", MO LECULES, vol. 21, no. 3, 2016, XP055654612, DOI: 10.3390/molecules21030333
Attorney, Agent or Firm:
KIM, Kyeongkyo et al. (KR)
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