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Title:
N-ALKYLSULFONYL-SUBSTITUTED AMIDE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2003/059871
Kind Code:
A1
Abstract:
It is intended to provide ACC activity inhibitor which are efficacious in treating obesity, hyperlipemia and fat liver seemingly induced by obesity, glucose tolerance failure, diabetes and diabetic complications (diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic great vessel disease, etc.) seemingly based on insulin resistance, hypertension and arteriosclerosis. N-Alkylsulfonyl-substituted amide derivatives, analogs thereof or pharmaceutically acceptable salts thereof have an efficacious ACC activity inhibitory effect.

Inventors:
SUZUKI NOBUYASU (JP)
NIHEI YUKIO (JP)
ICHINOSE HIDEHIRO (JP)
HATANAKA TOSHIHIRO (JP)
MAEZONO KATSUMI (JP)
OHSUMI KOJI (JP)
KONDO NOBUO (JP)
Application Number:
PCT/JP2003/000098
Publication Date:
July 24, 2003
Filing Date:
January 09, 2003
Export Citation:
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Assignee:
AJINOMOTO KK (JP)
SUZUKI NOBUYASU (JP)
NIHEI YUKIO (JP)
ICHINOSE HIDEHIRO (JP)
HATANAKA TOSHIHIRO (JP)
MAEZONO KATSUMI (JP)
OHSUMI KOJI (JP)
KONDO NOBUO (JP)
International Classes:
A61K45/00; A61K31/18; A61K31/426; A61K31/64; A61K38/28; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P13/12; A61P25/00; A61P27/02; A61P43/00; C07C311/51; C07D277/30; (IPC1-7): C07C311/51; A61K31/155; A61K31/18; A61K31/381; A61K31/4245; A61K31/426; A61K31/427; A61K31/4412; A61K31/4439; A61K31/64; A61K38/28; A61K45/00; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P13/12; A61P25/00; A61P27/02; A61P43/00; C07D213/82; C07D271/06; C07D277/30; C07D333/40; C07D417/04; C07D417/12
Domestic Patent References:
WO2000069432A12000-11-23
WO2000020358A22000-04-13
WO1995035308A11995-12-28
Foreign References:
JPH11171847A1999-06-29
JPH11171848A1999-06-29
JPH11171856A1999-06-29
Attorney, Agent or Firm:
Nakamura, Minoru (3-1 Marunouchi 3-Chom, Chiyoda-Ku Tokyo, JP)
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