Title:
N-HETERO-RING-SUBSTITUTED AMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2013/018675
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a compound having an excellent hypoglycemic activity and an excellent activity of protecting β cells or the pancreas, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition having an excellent therapeutic and/or prophylactic effect on type-1 diabetes, type-2 diabetes and the like in which glucose metabolism disorders occur to induce the increase in blood glucose levels.
A compound represented by general formula (I) or a pharmaceutically acceptable salt thereof.
Inventors:
YAMANOI SHIGEO
HATTA MADOKA
NAMIKI HIDENORI
MATSUMOTO KOJI
YOSHITOMI TOMOMI
HATTA MADOKA
NAMIKI HIDENORI
MATSUMOTO KOJI
YOSHITOMI TOMOMI
Application Number:
PCT/JP2012/069098
Publication Date:
February 07, 2013
Filing Date:
July 27, 2012
Export Citation:
Assignee:
DAIICHI SANKYO CO LTD (JP)
YAMANOI SHIGEO
HATTA MADOKA
NAMIKI HIDENORI
MATSUMOTO KOJI
YOSHITOMI TOMOMI
YAMANOI SHIGEO
HATTA MADOKA
NAMIKI HIDENORI
MATSUMOTO KOJI
YOSHITOMI TOMOMI
International Classes:
C07D413/12; A61K31/4245; A61P3/04; A61P3/10; A61P5/48; A61P43/00
Domestic Patent References:
WO2011016469A1 | 2011-02-10 | |||
WO2007116229A1 | 2007-10-18 | |||
WO2007003960A1 | 2007-01-11 | |||
WO2010001946A1 | 2010-01-07 | |||
WO2002046174A1 | 2002-06-13 | |||
WO2012050151A1 | 2012-04-19 | |||
WO2007116229A1 | 2007-10-18 | |||
WO2007003960A1 | 2007-01-11 | |||
WO2007003962A2 | 2007-01-11 | |||
WO2005061489A1 | 2005-07-07 | |||
WO2011016469A1 | 2011-02-10 | |||
WO2012050151A1 | 2012-04-19 |
Other References:
POVL KROGSGAARD-LARSEN ET AL.: "A Textbook of Drug Design and Development", 1996, HARWOOD ACADEMIC PUBLISHERS, pages: 351 - 385
BIOORG. MED. CHEM. LETT., vol. 12, 2002, pages 325 - 328
J. ORG. CHEM., vol. 62, 1997, pages 4197
JUNKO OGAWA ET AL., LIFE SCIENCES, vol. 65, no. 12, 1999, pages 1287 - 1296
See also references of EP 2738168A4
BIOORG. MED. CHEM. LETT., vol. 12, 2002, pages 325 - 328
J. ORG. CHEM., vol. 62, 1997, pages 4197
JUNKO OGAWA ET AL., LIFE SCIENCES, vol. 65, no. 12, 1999, pages 1287 - 1296
See also references of EP 2738168A4
Attorney, Agent or Firm:
ISHIBASHI Koki et al. (JP)
Kimiki Ishibashi (JP)
Kimiki Ishibashi (JP)
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Claims: