Title:
N-(SUBSTITUTED SULFONYL)BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/062848
Kind Code:
A1
Abstract:
The present invention discloses an N-(substituted sulfonyl)benzamide derivative, a preparation method therefor, and a pharmaceutical use thereof. Specifically, the present invention discloses an N-(substituted sulfonyl)benzamide derivative represented by a general formula (I), a preparation method therefor, and a pharmaceutically acceptable salt thereof, and their use as a therapeutic agent, particularly as Nav1.7 inhibitors. Definitions of the substituents in the general formula (I) are the same as those in the description.
Inventors:
GUAN DONGLIANG (CN)
WANG ZHONGLI (CN)
LIU ZHUBO (CN)
MENG LICHEN (CN)
ZHAO WEIFENG (CN)
LING LONG (CN)
WANG YAN (CN)
CHEN LEI (CN)
WANG ZHONGLI (CN)
LIU ZHUBO (CN)
MENG LICHEN (CN)
ZHAO WEIFENG (CN)
LING LONG (CN)
WANG YAN (CN)
CHEN LEI (CN)
Application Number:
PCT/CN2018/108316
Publication Date:
April 04, 2019
Filing Date:
September 28, 2018
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
International Classes:
C07D221/20; A61K31/397; A61K31/438; A61K31/445; A61P25/04; C07D205/04; C07D211/38
Domestic Patent References:
| WO2016124141A1 | 2016-08-11 | |||
| WO2011103196A1 | 2011-08-25 | |||
| WO2015051043A1 | 2015-04-09 |
Foreign References:
| CN105793238A | 2016-07-20 | |||
| CN107835805A | 2018-03-23 | |||
| CN105473554A | 2016-04-06 | |||
| CN104718188A | 2015-06-17 |
Attorney, Agent or Firm:
BOSS & YOUNG PATENT AND TRADEMARK LAW OFFICE (CN)
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