Title:
NANOEMULSION PREPARATION FOR TREATING MIGRAINES, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/077715
Kind Code:
A1
Abstract:
A method for preparing a nanoemulsion preparation for treating migraines comprises the following steps: selecting Angelicae sinensis radix and Chuanxiong rhizoma as raw materials, and extracting volatile oil by means of a supercritical extraction method, wherein the weight ratio of Angelicae sinensis radix to Chuanxiong rhizoma is 1:0.5-2; and selecting chitosan and alginate, loading the volatile oil on same by means of a single-emulsion solvent evaporation method to complete the preparation of a nanoemulsion, wherein the particle size of the nanoemulsion preparation is 200-300 nm. Further disclosed are a nanoemulsion preparation prepared by the above method and used for treating migraines, and the use of the nanoemulsion preparation prepared by the above method and used for treating migraines in the preparation of a food rproduct or a drug for treating migraines.
Inventors:
WANG YITAO (CN)
CHEN YULONG (CN)
ZHONG ZHANGFENG (CN)
WANG SHENGPENG (CN)
VONG CHI TENG (CN)
CHEN YULONG (CN)
ZHONG ZHANGFENG (CN)
WANG SHENGPENG (CN)
VONG CHI TENG (CN)
Application Number:
PCT/CN2022/083494
Publication Date:
May 11, 2023
Filing Date:
March 28, 2022
Export Citation:
Assignee:
UNIV MACAU (CN)
International Classes:
A61K9/107; A23L33/105; A61K36/236; A61K47/36; A61P25/06
Foreign References:
| CN113827563A | 2021-12-24 | |||
| CN106138212A | 2016-11-23 | |||
| CN112603934A | 2021-04-06 | |||
| CN1506044A | 2004-06-23 |
Other References:
"Doctoral Dissertation", 25 May 2007, SHENYANG PHARMACEUTICAL UNIVERSITY, CN, article FENG LILI: "Study on microemulsion administered intravenously with volatile oil of Angelica sinensis and Calyx calyx and its evaluation in vivo", pages: 1 - 139, XP009545524
Attorney, Agent or Firm:
FOUNDIN INTELLECTUAL PROPERTY (CN)
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