Title:
NANOPARTICLE COMPLEX FOR TREATING DISEASE, AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2020/231105
Kind Code:
A1
Abstract:
The present invention pertains to a nanoparticle complex for treating disease, and a method for producing same. More specifically, the present invention pertains to: a nanoparticle complex, wherein a tubular lipid structure is bonded to a portion of the surfaces of nanoparticles, thus enabling endocytosis as well as direct penetration through cell membranes, the nanoparticles can be effectively ingested into spheroid-type tumor cells due to the improved tissue penetration ability thereof, and a lipid structure of a sufficient length can be formed on the surfaces of the nanoparticles by controlling the ratio between a phospholipid bonded to a second reaction group that is used in the formation of the lipid structure and a phospholipid that is not bonded to the second reaction group; and a method for producing same.
Inventors:
KIM HYUN CHEOL (KR)
KIM DO YEON (KR)
KIM JEE WON (KR)
KIM DO YEON (KR)
KIM JEE WON (KR)
Application Number:
PCT/KR2020/006109
Publication Date:
November 19, 2020
Filing Date:
May 08, 2020
Export Citation:
Assignee:
UNIV SOGANG RES FOUNDATION (KR)
International Classes:
A61K9/51; A61K45/06; A61K48/00; A61P35/00
Foreign References:
| KR20140052812A | 2014-05-07 | |||
| KR101085203B1 | 2011-11-21 | |||
| KR20080094473A | 2008-10-23 | |||
| JP2017512840A | 2017-05-25 | |||
| US20190046446A1 | 2019-02-14 | |||
| KR20170040748A | 2017-04-13 | |||
| KR101880790B1 | 2018-08-16 |
Other References:
See also references of EP 3957305A4
Attorney, Agent or Firm:
KIM, Hyun Jin (KR)
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