NANOPARTICULATE FORMULATION FOR CANCER DISEASE TREATMENT

Title:

NANOPARTICULATE FORMULATION FOR CANCER DISEASE TREATMENT

Document Type and Number:

WIPO Patent Application WO/2017/170564

Kind Code:

A1

Abstract:

[Problem] To provide a novel DDS having SN-38 as the medicinal component. [Solution] An excellent SN-38 ester derivative with cancer cell proliferation inhibitory activity is provided which is effective in nanodrug production.

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Inventors:

KASAI HITOSHI (JP)
KOSEKI YOSHITAKA (JP)

Application Number:

PCT/JP2017/012669

Publication Date:

October 05, 2017

Filing Date:

March 28, 2017

Export Citation:

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Assignee:

UNIV TOHOKU (JP)

International Classes:

C07J43/00; A61K9/16; A61K31/4745; A61K31/58; A61P1/04; A61P1/16; A61P1/18; A61P11/00; A61P11/04; A61P13/08; A61P13/10; A61P15/00; A61P35/00; C07D491/22

Domestic Patent References:

WO2005118612A1	2005-12-15
WO2013188727A2	2013-12-19

Foreign References:

CN101967173A	2011-02-09
CN105315294A	2016-02-10
US20140135356A1	2014-05-15
US20080045559A1	2008-02-21

Other References:

WANG, HANGXIANG ET AL.: "Structure‐Based Rational Design of Prodrugs To Enable Their Combination with Polymeric Nanoparticle Delivery Platforms for Enhanced Antitumor Efficacy", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 53, no. 43, 2014, pages 11532 - 11537, XP055601540$

Attorney, Agent or Firm:

SHA Takuho (JP)

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