Title:
NANOPORE PROTEIN AND RELATED USE THEREOF IN SEQUENCING
Document Type and Number:
WIPO Patent Application WO/2023/123370
Kind Code:
A1
Abstract:
Provided in the present invention are a nanopore protein and the related use thereof in sequencing. The nanopore protein comprises: (a) a MP964 protein; or (b) a MP964 MUT protein; or (c) a protein subjected to substitution and/or deletion and/or addition of one or more amino acids at at least one of the following positions of the amino acid sequence of the protein in (a) or (b) and having a pore channel structure: position 97, position 98, position 127, position 143, and position 148; or (d) a protein having 80% or more homology with the amino acid sequence of the protein defined in any one of (a), (b) and (c) and having same function as the protein.
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Inventors:
DONG YULIANG (CN)
HU ZHAOLONG (CN)
WANG ZI (CN)
GUO FEI (CN)
LIU HUANHUAN (CN)
WU WEI (CN)
JI ZHOUXIANG (CN)
ZENG TAO (CN)
ZHANG WENWEI (CN)
XU XUN (CN)
HU ZHAOLONG (CN)
WANG ZI (CN)
GUO FEI (CN)
LIU HUANHUAN (CN)
WU WEI (CN)
JI ZHOUXIANG (CN)
ZENG TAO (CN)
ZHANG WENWEI (CN)
XU XUN (CN)
Application Number:
PCT/CN2021/143722
Publication Date:
July 06, 2023
Filing Date:
December 31, 2021
Export Citation:
Assignee:
BGI SHENZHEN (CN)
International Classes:
C07K14/35; A61K47/42; C12N15/00; C12Q1/6869; G01N27/26; G01N33/68
Foreign References:
| CN106459159A | 2017-02-22 | |||
| CN109295187A | 2019-02-01 | |||
| CN113480620A | 2021-10-08 | |||
| CN109207454A | 2019-01-15 | |||
| CN111499705A | 2020-08-07 | |||
| CN105372303A | 2016-03-02 |
Other References:
DATABASE Protein 6 October 2020 (2020-10-06), ANONYMOUS : "MspA family porin [Mycolicibacterium sp. P9-64]", XP093075951, retrieved from NCBI Database accession no. WP_149371538.1
Attorney, Agent or Firm:
KANGXIN PARTNERS, P.C. (CN)
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