Title:
NAPHTHOQUINONE OXIME COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/082817
Kind Code:
A1
Abstract:
The present application pertains to the technical field of pharmaceutical compounds and drugs, relates to an oxime-based naphthoquinone compound, a preparation method therefor and the uses thereof, and specifically relates to a formula (I), wherein the compound can act as a double-target selective inhibitor of STAT3 and IDO1, and is used for treating ovarian cancer, colon cancer, lung cancer and the like.
Inventors:
WANG HENGSHAN (CN)
JING XIAOTENG (CN)
HUANG RIZHEN (CN)
JIA QIANG (CN)
CHU CHANGHU (CN)
LV YUQUAN (CN)
JING XIAOTENG (CN)
HUANG RIZHEN (CN)
JIA QIANG (CN)
CHU CHANGHU (CN)
LV YUQUAN (CN)
Application Number:
PCT/CN2019/095516
Publication Date:
April 30, 2020
Filing Date:
July 11, 2019
Export Citation:
Assignee:
SEASONS BIOTECHNOLOGY TAIZHOU CO LTD (CN)
International Classes:
C07C237/20; A61K31/167; A61K31/255; A61K31/381; A61P35/00; C07C231/12; C07C249/08; C07C251/46; C07C381/00; C07D333/34
Foreign References:
| CN109438277A | 2019-03-08 | |||
| CN105622658A | 2016-06-01 |
Attorney, Agent or Firm:
SINO-CREATIVITY INTELLECTUAL PROPERTY LAW FIRM (CN)
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