NEURAL DIFFERENTIATION OF MESENCHYMAL STEM CELLS IN THERMOSENSITIVE HYDROGEL AND COMPOSITION FOR NEURAL DIFFERENTIATION

Title:

NEURAL DIFFERENTIATION OF MESENCHYMAL STEM CELLS IN THERMOSENSITIVE HYDROGEL AND COMPOSITION FOR NEURAL DIFFERENTIATION

Document Type and Number:

WIPO Patent Application WO/2013/119045

Kind Code:

A1

Abstract:

The present invention relates to the inducing of neural differentiation of mesenchymal stem cells (MSC) in a thermosensitive hydrogel, and to a composition for neural differentiation needed for inducing neural differentiation. More particularly, the present invention provides a cell delivery vehicle in injection form by culturing MSC and inducing neural differentiation in the thermosensitive hydrogel.

Inventors:

KIM MOON SUK (KR)
KWON JIN SEON (KR)
KIM DA YEON (KR)

Application Number:

PCT/KR2013/000976

Publication Date:

August 15, 2013

Filing Date:

February 07, 2013

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Assignee:

AJOU UNIV IND ACAD COOP FOUND (KR)

International Classes:

C12N11/04; A61K35/30; C12N5/0775; C12N5/079

Foreign References:

US20100040660A1	2010-02-18
KR20100044607A	2010-04-30
KR100687281B1	2007-02-27

Other References:

CHO, JAE HO ET AL.: "Chondrogenic differentiation of human mesenchymal stem cells using a thermosensitive poly(N-isopropylacrylamide) and water-soluble chitosan copolymer", BIOMATERIALS, vol. 25, no. 26, November 2004 (2004-11-01), pages 5743 - 5751, XP004508620
YAN, JIHONG ET AL.: "Biocompatibility Evaluation of Chitosan-based Injectable Hydrogels for the Culturing Mice Mesenchymal Stem Cells In Vitro", JOURNAL OF BIOMATERIALS APPLICATIONS, vol. 24, March 2010 (2010-03-01), pages 625 - 637, XP055079655

Attorney, Agent or Firm:

TW INTERNATIONAL PATENT LAW FIRM (KR)
특허법인 태웅 (KR)

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