Title:
NEURAMINIDASE INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/022448
Kind Code:
A1
Abstract:
The present invention belongs to the pharmaceutical field. Specifically, the present invention relates to a neuraminidase inhibitor compound as represented by formula (I), or a stereoisomer, a tautomer, a nitrogen oxide, a solvate, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition comprising the compound; and the use of the compound and the pharmaceutical composition thereof in the preparation of a drug for treating and/or preventing viral diseases or inhibiting neuraminidase activity. The compound provided can be released slowly, continuously and stably in vivo and a long-acting purpose is achieved.
Inventors:
CHEN HUIXUAN (CN)
KANG NING (CN)
LIU XIHONG (CN)
GUO CHEN (CN)
ZHANG JUFU (CN)
HE XIAOXI (CN)
WANG KUN (CN)
LI DEYAO (CN)
ZHANG LIJUN (CN)
KANG NING (CN)
LIU XIHONG (CN)
GUO CHEN (CN)
ZHANG JUFU (CN)
HE XIAOXI (CN)
WANG KUN (CN)
LI DEYAO (CN)
ZHANG LIJUN (CN)
Application Number:
PCT/CN2021/108383
Publication Date:
February 03, 2022
Filing Date:
July 26, 2021
Export Citation:
Assignee:
GUANGZHOU HENOVCOM BIOSCIENCE CO LTD (CN)
International Classes:
A61K31/215; C07C233/52; A61K31/22; A61K31/23; A61K31/337; A61K31/401; A61P31/16; C07C233/63; C07C235/14; C07C237/12; C07C279/16; C07D207/16; C07D305/08
Domestic Patent References:
| WO2001080892A1 | 2001-11-01 | |||
| WO2009129305A2 | 2009-10-22 | |||
| WO2013070118A1 | 2013-05-16 |
Foreign References:
| CN103108861A | 2013-05-15 | |||
| CN1272105A | 2000-11-01 | |||
| US5763483A | 1998-06-09 | |||
| CN104284884A | 2015-01-14 | |||
| CN104640540A | 2015-05-20 |
Other References:
DATABASE REGISTRY 9 August 2016 (2016-08-09), ANONYMOUS : "L-Valine, 1-[[[(3R,4R,5S)-4-(acetylamino)-5-[(aminoiminomethyl)amino]-3-(1- ethylpropoxy)-1-cyclohexen-1-yl]carbonyl]oxy]-2-methylpropyl ester (CA INDEX NAME)", XP055890986, retrieved from STN Database accession no. 1970223-82-5
Attorney, Agent or Firm:
GUANGZHOU SINO PATENT & TRADEMARK AGENT CO., LTD. (CN)
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