Title:
NEUROGENIC BAROREFLEX SENSITIVITY MEASUREMENT DEVICE, NEUROGENIC BAROREFLEX SENSITIVITY MEASUREMENT PROGRAM AND NEUROGENIC BAROREFLEX SENSITIVITY MEASUREMENT METHOD
Document Type and Number:
WIPO Patent Application WO/2014/157605
Kind Code:
A1
Abstract:
[Problem] To provide a neurogenic baroreflex sensitivity measurement device, neurogenic baroreflex sensitivity measurement program and neurogenic baroreflex sensitivity measurement method capable of easily and objectively measuring neurogenic baroreflex sensitivity that is not dependent on vascular hardness without using blood pressure or pulsations in the diameter of the carotid artery. [Solution] The neurogenic baroreflex sensitivity measurement device comprises: a pulse wave data-acquiring unit (41) for acquiring pulse wave data of an artery; a normalized pulse wave volume-calculating unit (42) for calculating a normalized pulse wave volume on the basis of the pulse wave data; a pulse interval-acquiring unit (43) for acquiring pulse intervals corresponding to the pulse wave data; a baroreflex series-detecting unit (44) for detecting baroreflex series in which the normalized pulse wave volume and pulse interval both increase or decrease for at least three beats in a row; and a neurogenic baroreflex sensitivity-calculating unit (45) for calculating the slope of a regression line representing the correlation between the normalized pulse wave volume and the pulse interval in a baroreflex series as the neurogenic baroreflex sensitivity, which is an index representing the neurogenic baroreflex function.
Inventors:
KATO YUICHI (JP)
Application Number:
PCT/JP2014/059081
Publication Date:
October 02, 2014
Filing Date:
March 28, 2014
Export Citation:
Assignee:
UNIV SAPPORO MEDICAL (JP)
International Classes:
A61B5/0245; A61B10/00
Domestic Patent References:
| WO2008105229A1 | 2008-09-04 |
Foreign References:
| JP2008086568A | 2008-04-17 | |||
| JP2011189080A | 2011-09-29 | |||
| JP2004041244A | 2004-02-12 | |||
| JP2008086568A | 2008-04-17 | |||
| JP5039123B2 | 2012-10-03 |
Other References:
BRIAN E. HUNT ET AL.: "Quantification of Mechanical and Neural Components of Vagal Baroreflex in Humans", HYPERTENSION, vol. 37, no. ISSUE., 2001, pages 1362 - 1368, XP055283384
MASASHI ICHINOSE ET AL.: "Modulation of arterial baroreflex dynamic response during mild orthostatic stress in humans", THE JOURNAL OF PHYSIOLOGY, vol. 557, no. ISSUE., 2004, pages 321 - 330, XP055283385
BRIAN E. HUNT ET AL.: "Quantification of Mechanical and Neural Components of Vagal Baroreflex in Humans, Hypertension", vol. 37, 2001, AMERICAN HEART ASSOCIATION, pages: 1362 - 1368
MASASHI ICHINOSE ET AL.: "Modulation of arterial baroreflex dynamic response during mild orthostatic stress in humans", THE JOURNAL OF PHYSIOLOGY, vol. 557, no. ISSUE., 2004, pages 321 - 330, XP055283385
BRIAN E. HUNT ET AL.: "Quantification of Mechanical and Neural Components of Vagal Baroreflex in Humans, Hypertension", vol. 37, 2001, AMERICAN HEART ASSOCIATION, pages: 1362 - 1368
Attorney, Agent or Firm:
SAGAWA Shingo et al. (JP)
Shingo Sagawa (JP)
Shingo Sagawa (JP)
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