Title:
A NEW CHEMICAL ENTITY USEFUL FOR TREATING VARIOUS DISEASES
Document Type and Number:
WIPO Patent Application WO/2014/055972
Kind Code:
A3
Abstract:
Novel chemical entities that inhibit the activity of human 5-lipoxygenase (5-LOX).
Inventors:
HOLMAN THEODORE (US)
MALONEY DAVID (US)
BANTUKALLU GANESHA RAI (US)
JADHAV AJIT (US)
SIMEONOV ANTON (US)
KELLY STEVEN L (US)
MALONEY DAVID (US)
BANTUKALLU GANESHA RAI (US)
JADHAV AJIT (US)
SIMEONOV ANTON (US)
KELLY STEVEN L (US)
Application Number:
PCT/US2013/063616
Publication Date:
May 30, 2014
Filing Date:
October 07, 2013
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
International Classes:
C07C211/51; A61K31/137; A61K31/4196; A61K31/497; A61K31/506; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P17/08; A61P27/14; A61P31/06; A61P31/10; A61P35/00; A61P37/08; C07C211/49; C07D249/08; C07D403/06; C07D405/14
Foreign References:
| EP0233461B2 | 2002-05-29 | |||
| JPS60252480A | 1985-12-13 |
Other References:
NOWACZYC, ALICJA ET AL.: "Triazole derivatives with anifungal activity: A pharmacophore model study.", DRUG RESEARCH, vol. 65, no. 6, pages 795 - 798
JERNEREN, FREDERIK.: "Novell Fatty Acid Dioxygenases of Human and Plant Pathogenic Fungi.", STUDIES BY GENE DELETION AND EXPRESSION. DIGITAL COMPREHENSIVE SUMMARIES OF UPPSALA DISSERTATIONS FROM THE FACULTY OF PHARMACY, vol. 135., 2011, pages 1 - 70
STEEL, H. C. ET AL.: "Itraconazole-mediated inhibition of calcium entry into platelet- activating factor-stimulated human neutrophils is due to interference with production of leukotriene B4.", CLINICAL AND EXPERIMENTAL IMMUNOLOGY, vol. 150, no. 1, 2007, pages 144 - 150
JERNEREN, FREDERIK.: "Novell Fatty Acid Dioxygenases of Human and Plant Pathogenic Fungi.", STUDIES BY GENE DELETION AND EXPRESSION. DIGITAL COMPREHENSIVE SUMMARIES OF UPPSALA DISSERTATIONS FROM THE FACULTY OF PHARMACY, vol. 135., 2011, pages 1 - 70
STEEL, H. C. ET AL.: "Itraconazole-mediated inhibition of calcium entry into platelet- activating factor-stimulated human neutrophils is due to interference with production of leukotriene B4.", CLINICAL AND EXPERIMENTAL IMMUNOLOGY, vol. 150, no. 1, 2007, pages 144 - 150
Attorney, Agent or Firm:
BELL, Adam, W. (58 West Portal Avenue # 121San Francisco, CA, US)
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