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Title:
NEW CRYSTALLINE FORM OF PIMAVANSERIN TARTRATE, PREPARATION METHOD THEREFOR, AND USE
Document Type and Number:
WIPO Patent Application WO/2018/049836
Kind Code:
A1
Abstract:
A polymorph III of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N'-[4-(2-methylpropoxy)phenylmethyl]urea tartrate, a preparation method therefor, and a medicinal use. Compared to the existing crystalline forms, the new crystalline form has clear advantages with respect to solubility, stability and the preparation process.

Inventors:
MENG XIAOMING (CN)
Application Number:
PCT/CN2017/084983
Publication Date:
March 22, 2018
Filing Date:
May 19, 2017
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Assignee:
SHANGHAI BEGREAT PHARMATECH (CN)
International Classes:
C07D211/58; A61K31/4468; A61P25/16; C07C51/43; C07C59/255
Domestic Patent References:
WO2008144326A22008-11-27
WO2006036874A12006-04-06
Foreign References:
CN104961671A2015-10-07
CN105523993A2016-04-27
CN104961672A2015-10-07
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