Title:
NEW LOW SIDE EFFECT PHARMACEUTICAL COMPOSITION CONTAINING ISONIAZID
Document Type and Number:
WIPO Patent Application WO/2010/009572
Kind Code:
A1
Abstract:
A new low side effect pharmaceutical composition containing pharmaceutical effective dosage isonizaid is provided. Pharmaceutical effective dosage P450 2E1 inhibitors are administrated in therapeutics, wherein the said P450 2E1 inhibitor is isoniazid. Additionally, a new low side effect pharmaceutical composition containing pharmaceutical effective dosage isonizaid is also provided. Pharmaceutical effective dosage disulfiram and bis-p-nitrophenyl phosphate are administrated in therapeutics.
Inventors:
HU YOAPU OLIVER (CN)
YOUNG TONHO (CN)
YOUNG TONHO (CN)
Application Number:
PCT/CN2008/001353
Publication Date:
January 28, 2010
Filing Date:
July 23, 2008
Export Citation:
Assignee:
NAT DEFENSE EDUCATION AND RES (CN)
HU YOAPU OLIVER (CN)
YOUNG TONHO (CN)
HU YOAPU OLIVER (CN)
YOUNG TONHO (CN)
International Classes:
A61K31/4409; A61K31/145; A61K31/21; A61P31/06
Foreign References:
| CN86104993A | 1987-08-26 | |||
| CN1616047A | 2005-05-18 | |||
| CN1602872A | 2005-04-06 |
Other References:
XUE HONGYUAN ET AL.: "Protective Effects of Baicalin on Hepatic Injury Induced by Combining Isoniazid with Rifampicin in mice.", PHARM J CHIN PLA(CN), vol. 19, no. 6, December 2003 (2003-12-01), pages 414 - 416
XUE HONGYUAN ET AL.: "Protective Effects of Silybin Capsules on Hepatic Injury Induced by Combining Isoniazid with Rifampin in mice.", CHINESE TRADITIONAL MEDICINE(CN), vol. 25, no. 4, April 2003 (2003-04-01), pages 307 - 310
DATABASE CA 2004, SPRACKLIN, D. K.; ET AL.: "Concardance between trifluoroacetic acid and hepatic protein trifluoroacetylation after disulfiram inhibition of halothane metabolism in rats.", Database accession no. 140:35344
XUE HONGYUAN ET AL.: "Protective Effects of Silybin Capsules on Hepatic Injury Induced by Combining Isoniazid with Rifampin in mice.", CHINESE TRADITIONAL MEDICINE(CN), vol. 25, no. 4, April 2003 (2003-04-01), pages 307 - 310
DATABASE CA 2004, SPRACKLIN, D. K.; ET AL.: "Concardance between trifluoroacetic acid and hepatic protein trifluoroacetylation after disulfiram inhibition of halothane metabolism in rats.", Database accession no. 140:35344
Attorney, Agent or Firm:
ADVANCE CHINA I. P. LAW OFFICE (MinhuiSuite 918-920, 9/F., Dong Shan Plaza, No.69 Xianlie Central Roa, Guangzhou Guangdong 5, CN)
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