Title:
NEW NAPHTHALENE COMPOUNDS AND METHOD OF PRODUCING THE SAME
Document Type and Number:
WIPO Patent Application WO/1990/012004
Kind Code:
A1
Abstract:
Naphthalene compounds represented by general formula (I), and pharmaceutically acceptable salts thereof, useful as a phospholipase A¿2? inhibitor and an antiinflammatory agent; wherein R?1¿ represents hydrogen, lower alkyl or amino-protective group; R?2¿ and R?3¿ represent each hydrogen or halogen; and A represents lower alkylene. The invention further discloses a method of producing these compounds, pharmaceutical preparations containing the same as the active ingredient, and a method of preventing and/or treating inflammatory diseases of man and animal.
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Inventors:
NAMIKI TAKAYUKI (JP)
KATAYAMA AKIRA (JP)
HEMMI KEIJI (JP)
HASHIMOTO MASASHI (JP)
KATAYAMA AKIRA (JP)
HEMMI KEIJI (JP)
HASHIMOTO MASASHI (JP)
Application Number:
PCT/JP1990/000466
Publication Date:
October 18, 1990
Filing Date:
April 06, 1990
Export Citation:
Assignee:
FUJISAWA PHARMACEUTICAL CO (JP)
International Classes:
C07D207/08; (IPC1-7): A61K31/40; C07D207/08
Foreign References:
| JPS495963A | 1974-01-19 | |||
| JPS5639065A | 1981-04-14 | |||
| JPS60163861A | 1985-08-26 |
Attorney, Agent or Firm:
Aoki, Takashi (Osaka Factory, 1-6, Kashima 2-chome, Yodogawa-k, Osaka-shi Osaka 532, JP)
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