NITROGEN-CONTAINING CHAIN COMPOUND, PREPARATION METHOD THEREFOR, COMPOSITION CONTAINING SAID COMPOUND, AND USE THEREOF

Title:

NITROGEN-CONTAINING CHAIN COMPOUND, PREPARATION METHOD THEREFOR, COMPOSITION CONTAINING SAID COMPOUND, AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2024/032754

Kind Code:

A1

Abstract:

Disclosed are a nitrogen-containing chain compound, a preparation method therefor, a composition containing said compound, and a use thereof. Provided is a nitrogen-containing chain compound as represented by formula (I) or a pharmaceutically acceptable salt thereof. The nitrogen-containing chain compound represented by formula (I) can be used for preparing a lipid carrier. The prepared lipid carrier can encapsulate a nucleic acid drug, and may be used for delivering a nucleic acid prophylactic agent and/or therapeutic agent to mammalian cells and organs and producing an effect.

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Inventors:

LIN JINZHONG (CN)
LU JING (CN)
YU HANG (CN)
JIANG TING (CN)
ZHANG FAN (CN)
ZHANG BOYANG (CN)
GUO JUNXIANG (CN)
CHEN LIN (CN)
WANG BING (CN)

Application Number:

PCT/CN2023/112483

Publication Date:

February 15, 2024

Filing Date:

August 11, 2023

Export Citation:

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Assignee:

SHANGHAI RNACURE BIOPHARMA CO LTD (CN)

International Classes:

C07C237/08; A61K47/18; C07C219/02

Foreign References:

CN107708739A	2018-02-16
CN1193316A	1998-09-16
US20020007073A1	2002-01-17

Other References:

DATABASE REGISTRY 31 August 1990 (1990-08-31), ANONYMOUS : "L-Glutamic acid, N-(3-am ino-1-oxopropyl)-, di tetradecyl ester (9C I) (CA INDEX NAME)", XP093138311, retrieved from STN Database accession no. 129064-78-4

Attorney, Agent or Firm:

SHANGHAI BESHINING LAW OFFICE (CN)

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