Title:
NITROGEN-CONTAINING HETEROCYCLIC AUTOTAXIN INHIBITOR, AND COMPOSITION CONTAINING SAME AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/115375
Kind Code:
A1
Abstract:
Disclosed are a nitrogen-containing heterocyclic compound as shown in formula (I), or a stereoisomer, a solvate, a deuterated compound, a pharmaceutically acceptable salt, or a eutectic thereof or a pharmaceutical composition containing same, and the use thereof in the preparation of a drug for treating/preventing diseases mediated by autotaxin. Each group in formula (I) is as defined in the description.
Inventors:
LI YAO (CN)
SHI ZONGJUN (CN)
WANG WENJING (CN)
WANG YONGLI (CN)
PEI YUNPENG (CN)
SONG CHANGWEI (CN)
LI YONGHONG (CN)
TANG PINGMING (CN)
YU YAN (CN)
ZHANG CHEN (CN)
NI JIA (CN)
YAN PANGKE (CN)
SHI ZONGJUN (CN)
WANG WENJING (CN)
WANG YONGLI (CN)
PEI YUNPENG (CN)
SONG CHANGWEI (CN)
LI YONGHONG (CN)
TANG PINGMING (CN)
YU YAN (CN)
ZHANG CHEN (CN)
NI JIA (CN)
YAN PANGKE (CN)
Application Number:
PCT/CN2020/135220
Publication Date:
June 17, 2021
Filing Date:
December 10, 2020
Export Citation:
Assignee:
SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D471/04; A61K31/437; A61K31/506; A61P39/00; C07D471/10
Foreign References:
| CN109476664A | 2019-03-15 | |||
| CN105102458A | 2015-11-25 | |||
| CN105143218A | 2015-12-09 | |||
| US20170044133A1 | 2017-02-16 | |||
| CN109476664A | 2019-03-15 |
Other References:
S. R. SANDLER ET AL.: "Organic Functional Group Preparations", 1983, JOHN WILEY & SONS, INC.
H. O. HOUSE: "Modern Synthetic Reactions", 1972, W. A. BENJAMIN, INC.
T. L. GILCHRIST: "Advanced Organic Chemistry: Reactions, Mechanisms, and Structure", 1992, WILEY-INTERSCIENCE
FUHRHOP, J.PENZLIN G: "Organic Synthesis: Concepts, Methods, Starting Materials", 1994, JOHN WILEY & SONS
HOFFMAN, RV: "Organic Chemistry, An Intermediate Text", 1996, OXFORD UNIVERSITY PRESS
LAROCK, R. C.: "Industrial Organic Chemicals: Starting Materials and Intermediates: An Ullmann's Encyclopedia", 1999, JOHN WILEY & SONS
SOLOMONS, T. W. G: "Modern Carbonyl Chemistry", 2000, JOHN WILEY & SONS
STOWELL, J.C.: "Intermediate Organic Chemistry", 1993, WILEY-INTERSCIENCE
"Chemistry of Functional Groups", JOHN WILEY & SONS
See also references of EP 4074711A4
H. O. HOUSE: "Modern Synthetic Reactions", 1972, W. A. BENJAMIN, INC.
T. L. GILCHRIST: "Advanced Organic Chemistry: Reactions, Mechanisms, and Structure", 1992, WILEY-INTERSCIENCE
FUHRHOP, J.PENZLIN G: "Organic Synthesis: Concepts, Methods, Starting Materials", 1994, JOHN WILEY & SONS
HOFFMAN, RV: "Organic Chemistry, An Intermediate Text", 1996, OXFORD UNIVERSITY PRESS
LAROCK, R. C.: "Industrial Organic Chemicals: Starting Materials and Intermediates: An Ullmann's Encyclopedia", 1999, JOHN WILEY & SONS
SOLOMONS, T. W. G: "Modern Carbonyl Chemistry", 2000, JOHN WILEY & SONS
STOWELL, J.C.: "Intermediate Organic Chemistry", 1993, WILEY-INTERSCIENCE
"Chemistry of Functional Groups", JOHN WILEY & SONS
See also references of EP 4074711A4
Attorney, Agent or Firm:
WU, FENG & ZHANG (CN)
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