Title:
NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/067691
Kind Code:
A1
Abstract:
Disclosed are a nitrogen-containing heterocyclic compound and pharmaceutical use thereof. Specifically, disclosed are a nitrogen-containing heterocyclic compound represented by general formula (I), a preparation method therefor, a pharmaceutical composition comprising the compound, and use of the compound as a poly(ADP-ribose) polymerase 1 (PARP1) inhibitor for treating diseases related to PARP1 activity. Substituents in general formula (I) have the same definitions as those in the description.
Inventors:
WANG GUOZHENG (CN)
LIU GUOBIAO (CN)
YAN XU (CN)
LI BIN (CN)
REN YUE (CN)
LIU YANXIN (CN)
WU YONG (CN)
ZHAO LIKUN (CN)
LIU GUOBIAO (CN)
YAN XU (CN)
LI BIN (CN)
REN YUE (CN)
LIU YANXIN (CN)
WU YONG (CN)
ZHAO LIKUN (CN)
Application Number:
PCT/CN2023/121994
Publication Date:
April 04, 2024
Filing Date:
September 27, 2023
Export Citation:
Assignee:
THE NAT INSTITUTES OF PHARMACEUTICAL R & D CO LTD (CN)
International Classes:
C07D519/00; A61K31/444; A61P9/10; C07D471/04
Domestic Patent References:
| WO2023207283A1 | 2023-11-02 | |||
| WO2023036285A1 | 2023-03-16 | |||
| WO2023046034A1 | 2023-03-30 | |||
| WO2023051812A1 | 2023-04-06 | |||
| WO2022228387A1 | 2022-11-03 | |||
| WO2023056039A1 | 2023-04-06 | |||
| WO2023146957A1 | 2023-08-03 | |||
| WO2021260092A1 | 2021-12-30 |
Foreign References:
| CN116891456A | 2023-10-17 | |||
| CN115232154A | 2022-10-25 | |||
| CN115232121A | 2022-10-25 | |||
| CN116143776A | 2023-05-23 | |||
| CN116535401A | 2023-08-04 | |||
| CN114144413A | 2022-03-04 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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