Title:
NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/247770
Kind Code:
A1
Abstract:
A nitrogen-containing heterocyclic compound, a preparation method therefor and an application thereof. A nitrogen-containing heterocyclic compound represented by formula I, a pharmaceutically acceptable salt thereof, a stereoisomer thereof, a tautomer thereof, or an isotopic compound thereof. The nitrogen-containing heterocyclic compound is expected to be used for the treatment and/or prevention of multiple diseases related to Ras.
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Inventors:
XU ZUSHENG (CN)
LOU YANGTONG (CN)
SHEN JIAN (CN)
XIE TIEGANG (CN)
SUN QINGRUI (CN)
CHEN LI (CN)
ZENG KUN (CN)
JIN XIN (CN)
LOU YANGTONG (CN)
SHEN JIAN (CN)
XIE TIEGANG (CN)
SUN QINGRUI (CN)
CHEN LI (CN)
ZENG KUN (CN)
JIN XIN (CN)
Application Number:
PCT/CN2022/094364
Publication Date:
December 01, 2022
Filing Date:
May 23, 2022
Export Citation:
Assignee:
SHANGHAI YINGLI PHARM CO LTD (CN)
International Classes:
C07D403/02; A61K31/41; A61K31/4188; A61K31/498; A61K31/4985; A61P35/00; C07D239/84; C07D401/04; C07D403/04; C07D487/04; C07D498/04
Domestic Patent References:
| WO2021231526A1 | 2021-11-18 | |||
| WO2017172979A1 | 2017-10-05 | |||
| WO2021041671A1 | 2021-03-04 |
Foreign References:
| CN104557872A | 2015-04-29 | |||
| US20170247376A1 | 2017-08-31 | |||
| CN110267957A | 2019-09-20 | |||
| CN112574224A | 2021-03-30 | |||
| CN202110567504A | 2021-05-24 | |||
| CN202111153102A | 2021-09-29 | |||
| CN202210017287A | 2022-01-07 |
Other References:
NATURE, vol. 503, 2013, pages 548 - 551
SCIENCE, vol. 351, 2016, pages 604 - 608
R. LAROCK: "Comprehensive Organic Transformations", 1989, VCH PUBLISHERS
T. W. GREENEP. G. M. WUTS: "Protective Groups in Organic Synthesis,", 1999, JOHN WILEY AND SONS
L. FIESERM. FIESER: "Fieser and Fieser's Reagents for Organic Synthesis", 1994, JOHN WILEY AND SONS
"Encyclopedia of Reagents for Organic Synthesis", 1995, JOHN WILEY AND SONS
BERGE ET AL.: "Pharmaceutical Salts", JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 66, 1977, pages 1 - 19, XP002675560, DOI: 10.1002/jps.2600660104
"Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
SCIENCE, vol. 351, 2016, pages 604 - 608
R. LAROCK: "Comprehensive Organic Transformations", 1989, VCH PUBLISHERS
T. W. GREENEP. G. M. WUTS: "Protective Groups in Organic Synthesis,", 1999, JOHN WILEY AND SONS
L. FIESERM. FIESER: "Fieser and Fieser's Reagents for Organic Synthesis", 1994, JOHN WILEY AND SONS
"Encyclopedia of Reagents for Organic Synthesis", 1995, JOHN WILEY AND SONS
BERGE ET AL.: "Pharmaceutical Salts", JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 66, 1977, pages 1 - 19, XP002675560, DOI: 10.1002/jps.2600660104
"Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
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