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Title:
NITROGEN HETEROARYL AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/082921
Kind Code:
A1
Abstract:
Provided are a nitrogen heteroaryl amide derivative having the structure of formula (I), a preparation method therefor, and application thereof. Definitions of various substituents are as described in the specification and the claims. The series of compounds can be widely applied to preparation of drugs for treating one or more tumors, cancers, metabolic diseases, and autoimmune diseases or disorders, and are expected to be developed as a new generation of RORγt agonist drugs.

Inventors:
ZHAO BAOWEI (CN)
XUN GUOLIANG (CN)
WEI MINGSONG (CN)
ZHANG MINGMING (CN)
YANG SHUQUN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
Application Number:
PCT/CN2019/104957
Publication Date:
April 30, 2020
Filing Date:
September 09, 2019
Export Citation:
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Assignee:
ABBISKO THERAPEUTICS CO LTD (CN)
International Classes:
C07D401/14; A61K31/4184; A61P35/00; C07D231/56; C07D401/04; C07D401/06; C07D401/12; C07D471/04
Domestic Patent References:
WO2017132432A12017-08-03
WO2013019682A12013-02-07
Foreign References:
CN108463458A2018-08-28
CN103384668A2013-11-06
US20170260180A12017-09-14
Other References:
DATABASE REGISTRY 12 May 2016 (2016-05-12), XP055710666, retrieved from STN Database accession no. 1908907-64-1
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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