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Title:
NLRP3 INFLAMMASOME INHIBITORS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/094150
Kind Code:
A1
Abstract:
Described herein are NOD-like receptor protein 3 (NLRP3) inflammasome inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with NLRP3 inflammasome pathway.

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Inventors:
LIU YINGTAO (CN)
WU JIANPING (CN)
DING XIAOYU (CN)
QIN LUOHENG (CN)
LI CHAOPENG (CN)
Application Number:
PCT/CN2023/129502
Publication Date:
May 10, 2024
Filing Date:
November 03, 2023
Export Citation:
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Assignee:
INSILICO MEDICINE IP LTD (CN)
International Classes:
C07D253/07; A61K31/50; A61K31/5025; A61P3/10; A61P19/02; A61P25/16; C07D253/06; C07D253/10; C07D487/04; C07D487/06
Domestic Patent References:
WO2022230912A12022-11-03
WO2022166890A12022-08-11
WO2022060951A12022-03-24
Foreign References:
CN116102535A2023-05-12
CN116410140A2023-07-11
TW202231281A2022-08-16
CN113784957A2021-12-10
US3873543A1975-03-25
GB1492073A1977-11-16
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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