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Title:
NON-AQUEOUS PREPARATION WITH EXCELLENT STABILITY
Document Type and Number:
WIPO Patent Application WO/2024/005178
Kind Code:
A1
Abstract:
The present invention provides a non-aqueous preparation that comprises 5-ALA, a derivative thereof, or a salt of these, and that has excellent stability of the 5-ALA, the derivative, or the salt of these. A non-aqueous preparation according to the present invention comprises: a compound represented by general formula (I) or a salt thereof; a sugar or a sugar alcohol; and at least one substance selected from the group consisting of fatty acids, fatty acid esters, aliphatic hydrocarbons, and aliphatic alcohols with a melting point of 30-100°C. [In general formula (I), R1 represents a hydrogen atom or an acyl group, and R2 represents a hydrogen atom, a linear or branched alkyl group, a cycloalkyl group, an aryl group, or an aralkyl group.]

Inventors:
DEKI TAKESHI (JP)
ISHII KUNIAKI (JP)
HORAGUCHI HARUHIKO (JP)
YAMASHITA TOMONORI (JP)
Application Number:
PCT/JP2023/024334
Publication Date:
January 04, 2024
Filing Date:
June 30, 2023
Export Citation:
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Assignee:
NEOPHARMA JAPAN CO LTD (JP)
International Classes:
A61K31/197; A61K9/14; A61K9/16; A61K9/20; A61K9/48; A61K31/22; A61K47/02; A61K47/04; A61K47/06; A61K47/10; A61K47/12; A61K47/14; A61P1/08; A61P7/06; A61P43/00
Domestic Patent References:
WO2019230939A12019-12-05
Foreign References:
JP2015054836A2015-03-23
JPH05112488A1993-05-07
JP2012031163A2012-02-16
JP2010240078A2010-10-28
KR20110138709A2011-12-28
Attorney, Agent or Firm:
SAEKI, Takuro et al. (JP)
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