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Title:
NON-HUMAN ANIMAL WITH HUMANIZED MODIFICATION OF TLR7 AND/OR TLR8 GENE
Document Type and Number:
WIPO Patent Application WO/2024/012578
Kind Code:
A1
Abstract:
A non-human animal expressing a human or chimeric TLR7 and/or TLR8 protein, and a usage method therefor.

Inventors:
ZHANG SHUJIN (CN)
ZHOU XIAOFEI (CN)
YAO JIAWEI (CN)
Application Number:
PCT/CN2023/107520
Publication Date:
January 18, 2024
Filing Date:
July 14, 2023
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Assignee:
BIOCYTOGEN PHARMACEUTICALS BEIJING CO LTD (CN)
International Classes:
A01K67/027; C07K19/00; C12N5/10; C12N15/62; C12N15/85
Foreign References:
CN113651892A2021-11-16
CN113373178A2021-09-10
CN101423865A2009-05-06
US20050235372A12005-10-20
Other References:
DATABASE Nucleotide 15 May 2022 (2022-05-15), ANONYMOUS: "Homo Sapiens Toll Like Receptor 7 (TLR7), RefSeqGene on Chromosome X", XP093127353, retrieved from NCBI Database accession no. NG_012569.1
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