Title:
NON-IMPLANTABLE MEDICAL DEVICE COATED WITH ENCAPSULATED NANOPARTICLES CONTAINING THERAPEUTIC AGENTS
Document Type and Number:
WIPO Patent Application WO/2010/140163
Kind Code:
A3
Abstract:
A drug-delivering medical device for delivering a drug to a target site in a body lumen is disclosed. The drug-delivering medical device includes a balloon catheter and an inflatable balloon positioned on the balloon catheter. The inflatable balloon has a hydrophilic surface. One or more portions of the hydrophilic surface are coated with two or more nano-carriers. A nano-carrier of the two or more nano-carriers includes a drug surrounded by an encapsulating medium. As the drug is surrounded by the encapsulating medium, the surface of the nano-carrier is devoid of the drug. When the inflatable balloon is inflated upon coming in proximity to a target site in the body lumen, about 30% to 80% of the two or more nano-carriers are released from the hydrophilic surface within 15-90 seconds.
Inventors:
DOSHI MANISH (IN)
SHERDIWALA DIVYESH (IN)
SOJITRA PRAKASH (IN)
VYAS ASHWIN (IN)
GANDHI PANKAJ (IN)
SHERDIWALA DIVYESH (IN)
SOJITRA PRAKASH (IN)
VYAS ASHWIN (IN)
GANDHI PANKAJ (IN)
Application Number:
PCT/IN2010/000349
Publication Date:
January 27, 2011
Filing Date:
May 21, 2010
Export Citation:
Assignee:
CONCEPT MEDICAL INC (US)
DOSHI MANISH (IN)
SHERDIWALA DIVYESH (IN)
SOJITRA PRAKASH (IN)
VYAS ASHWIN (IN)
GANDHI PANKAJ (IN)
DOSHI MANISH (IN)
SHERDIWALA DIVYESH (IN)
SOJITRA PRAKASH (IN)
VYAS ASHWIN (IN)
GANDHI PANKAJ (IN)
International Classes:
A61K47/14; A61M25/04; A61L29/16; A61M25/10; A61M29/02
Domestic Patent References:
| WO2009018816A2 | 2009-02-12 | |||
| WO2004028582A1 | 2004-04-08 |
Foreign References:
| US20030064965A1 | 2003-04-03 | |||
| US20080118544A1 | 2008-05-22 | |||
| US6656156B2 | 2003-12-02 | |||
| US5603991A | 1997-02-18 | |||
| CN101309706A | 2008-11-19 |
Other References:
PENDYALA,LAKSHMANA ET AL.: "Passive and active polymer coatings for intracoronary stents: novel devices to promote arterial healing", JOURNAL OF INTERVENTIONAL CARDIOLOGY, vol. 22, no. 1, 2009, pages 37 - 48
Attorney, Agent or Firm:
RAJENDRAN, Arun (G-01 Prestige Loka,7/1, Brunton Road, Bangalore 5, IN)
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