Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
NOVEL AMIDE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2001/068585
Kind Code:
A1
Abstract:
A compound represented by the general formula (I) and a salt thereof: R?1¿-A-X-NHCO-Y-R?2¿ wherein R?1¿ is an optionally substituted heterocyclic group or optionally substituted phenyl; R?2¿ is optionally substituted fused phenyl, optionally substituted phenyl, or optionally substituted thienyl; A is a group represented by the formula -(CH¿2?)¿t?-(O)¿m?- or (wherein R?3¿ and R?4¿ each is hydrogen or R?3¿ and R?4¿ in combination form imino; R?5¿ is hydrogen or lower alkyl; t is 0, 1, or 2; and p, m, and n each is 0 or 1); X is optionally substituted phenylene or an optionally substituted, divalent, nitrogenous heterocyclic group; and Y is a bond, lower alkylene, or lower alkenylene.

Inventors:
YAMADA AKIRA (JP)
TOMISHIMA MASAKI (JP)
HAYASHIDA HISASHI (JP)
IMANISHI MASASHI (JP)
SPEARS GLEN W (JP)
ITO KIYOTAKA (JP)
TAKAHASHI FUMIE (JP)
MIYAKE HIROSHI (JP)
Application Number:
PCT/JP2001/001993
Publication Date:
September 20, 2001
Filing Date:
March 13, 2001
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
FUJISAWA PHARMACEUTICAL CO (JP)
YAMADA AKIRA (JP)
TOMISHIMA MASAKI (JP)
HAYASHIDA HISASHI (JP)
IMANISHI MASASHI (JP)
SPEARS GLEN W (JP)
ITO KIYOTAKA (JP)
TAKAHASHI FUMIE (JP)
MIYAKE HIROSHI (JP)
International Classes:
C07C205/12; C07C233/75; C07C257/18; C07C311/08; C07D209/08; C07D209/18; C07D213/30; C07D213/38; C07D213/40; C07D213/56; C07D213/65; C07D213/73; C07D213/74; C07D213/75; C07D213/82; C07D213/89; C07D215/38; C07D217/22; C07D233/54; C07D235/18; C07D235/30; C07D237/20; C07D239/26; C07D239/42; C07D249/14; C07D253/07; C07D261/14; C07D261/20; C07D263/32; C07D277/30; C07D277/42; C07D277/64; C07D285/135; C07D295/185; C07D311/22; C07D333/38; C07D401/04; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D521/00; C07D285/12; (IPC1-7): C07C233/75; C07C233/80; C07C233/81; C07C257/14; C07C257/18; C07C257/20; C07D233/64; C07D249/08; C07D239/26; C07D213/75; C07D231/12; C07D217/22; C07D333/20; C07D277/28; C07D263/32; C07D233/36; C07D215/12; C07D209/08; C07D405/12; C07D403/12; A61K31/167; A61K31/4164
Domestic Patent References:
WO1996023783A11996-08-08
WO1996023769A21996-08-08
WO1995030675A11995-11-16
WO1995006044A11995-03-02
WO1995004729A11995-02-16
WO1998042696A11998-10-01
WO1995005363A11995-02-23
WO1994021621A11994-09-29
WO2000006550A12000-02-10
Foreign References:
JPH11130750A1999-05-18
JPH0476530A1992-03-11
JPH03282536A1991-12-12
GB1007334A1965-10-13
JPH11349572A1999-12-21
Other References:
KALKMAN HANS O.: "Cataleptogenic effect of subtype selective 5-HT receptor antagonists in the rat", EUR. J. PHARMACOL., vol. 343, no. 2/3, 1998, pages 201 - 207, XP002942999
MANUEL N.A.: "Ketanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord", BR. J. PHARMACOL., vol. 116, no. 6, 1995, pages 2647 - 2654, XP002943000
KORBONITS DEZSO ET AL.: "Synthesis of 4-aminopyrimidines from 1,2,4-oxadiazoles. I. New general method for the preparation of 4-aminoquinazolines and their hetero analogs", CHEM. BER., vol. 117, no. 11, 1984, pages 3183 - 3193, XP002943401
See also references of EP 1264820A4
Attorney, Agent or Firm:
Yoshikawa, Toshio (6F 9-19, Higashinoda-cho 4-chome Miyakojima-ku Osaka-shi Osaka, JP)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: MIXTURES OF SEMI-ESTERS OF POLYBASIC ORGANIC ACIDS AND LONG-CHAIN ALKANOLS, THE PRODUCTION AND THE U...

Next Patent: $g(a)¿4?$g(b)¿1? AND $g(a)¿4?$g(b)¿7? INTEGRIN INHIBITORS