Title:
NOVEL AMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2008/139845
Kind Code:
A1
Abstract:
Disclosed is an amide derivative having an excellent SCD inhibitory activity or a pharmacologically acceptable salt thereof. Specifically disclosed is an amide derivative represented by the general formula (I) below, or a pharmacologically acceptable salt thereof. [chemical formula 1] (I) (In the formula, R1 represents a hydroxy group, a C1-C6 alkoxy group, a C2-C6 hydroxyalkoxy group or the like; R2 represents a hydroxy group, a C1-C6 alkoxy group, a C2-C6 hydroxyalkoxy group or the like; R3 represents a hydrogen atom or the like; R4 represents a C6-C10 aryl group which may be substituted at one to five positions independently by a group selected from the substituent group A, or the like; V represents a group represented by the formula: -NH- or a single bond; W represents a group represented by the formula: -NH- or a single bond; T represents a group represented by the formula: =C(R5)- or a nitrogen atom; and Q represents a group represented by the formula: =C(R6)- or a nitrogen atom.)
Inventors:
UTO YOSHIKAZU
KIYOTSUKA YOHEI
KURATA HITOSHI
OGATA TSUNEAKI
OKUYAMA RYO
ABE MANABU
HARADA JUN
KONO KEITA
KIYOTSUKA YOHEI
KURATA HITOSHI
OGATA TSUNEAKI
OKUYAMA RYO
ABE MANABU
HARADA JUN
KONO KEITA
Application Number:
PCT/JP2008/057711
Publication Date:
November 20, 2008
Filing Date:
April 22, 2008
Export Citation:
Assignee:
DAIICHI SANKYO CO LTD (JP)
UTO YOSHIKAZU
KIYOTSUKA YOHEI
KURATA HITOSHI
OGATA TSUNEAKI
OKUYAMA RYO
ABE MANABU
HARADA JUN
KONO KEITA
UTO YOSHIKAZU
KIYOTSUKA YOHEI
KURATA HITOSHI
OGATA TSUNEAKI
OKUYAMA RYO
ABE MANABU
HARADA JUN
KONO KEITA
International Classes:
C07D277/20; A61K31/426; A61K31/433; A61K31/5377; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P7/00; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P13/12; A61P15/00; A61P19/02; A61P19/06; A61P25/00; A61P25/04; A61P27/02; A61P27/12; A61P43/00; C07D277/46; C07D277/56; C07D285/12; C07D285/135; C07D333/36
Domestic Patent References:
| WO2007044085A2 | 2007-04-19 | |||
| WO2007009236A1 | 2007-01-25 | |||
| WO2006130986A1 | 2006-12-14 | |||
| WO2007130075A1 | 2007-11-15 | |||
| WO2008044767A1 | 2008-04-17 |
Foreign References:
| JP2004501146A | 2004-01-15 | |||
| JP2006513192A | 2006-04-20 |
Other References:
LADWA K. ET AL.: "Synthesis and antimicrobial activity of some aryl amide and sulphonamide derivatives bearing thiadiazole nucleus", ORIENTAL JOURNAL OF CHEMISTRY, vol. 18, no. 1, 2002, pages 135 - 138
Attorney, Agent or Firm:
ISHIBASHI, Koki et al. (LIMITED1-16-13, Kitakasa, Edogawa-ku Tokyo 81, JP)
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