NOVEL ANTIANDROGENIC AGENT

WIPO Patent Application WO/2002/002589

A1

A compound represented by the general formula (I) useful as an antiandrogenic agent, a pharmacologically acceptable salt thereof, or a prodrug comprising either of these: (I) wherein X?1¿ and X?2¿ each independently represents hydrogen or a substituent such as, e.g., R?a¿ represents hydrogen or a hydroxyl-protecting group; R?b¿ and R?c¿ in combination represent optionally protected -(C=O)- in cooperation with the 3-position carbon atom bonded to these; and the broken line indicates a single bond or double bond in cooperation with the solid line.

JP2013071913	ANGIOGENESIS, FORMING OR STABILIZING AGENT FOR LYMPHATIC VESSEL
JP2000505419	[Title of Invention] Male contraceptive graft
JP2001122768	POWDERY MEDICINAL COMPOSITION FOR DELIVERING MEDICINE TO BRAIN

OHTA MASATERU (JP)
KATO NOBUAKI (JP)
NAKAMURA MITSUAKI (JP)
TACHIBANA KAZUTAKA (JP)

PCT/JP2001/005724

January 10, 2002

July 02, 2001

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CHUGAI PHARMACEUTICAL CO LTD (JP)
OHTA MASATERU (JP)
KATO NOBUAKI (JP)
NAKAMURA MITSUAKI (JP)
TACHIBANA KAZUTAKA (JP)

A61K31/565; A61P13/08; A61P15/00; A61P17/00; A61P17/08; A61P17/14; A61P35/00; C07J1/00; C07J41/00; (IPC1-7): C07J41/00; A61K31/565; A61P13/08; A61P15/00; A61P17/00; A61P17/08; A61P17/14; A61P35/00; C07J1/00

WO1995017192A1	1995-06-29
WO1991000732A1	1991-01-24
WO1991000733A1	1991-01-24
WO1998025916A1	1998-06-18
WO1997049709A1	1997-12-31
WO1995017192A1	1995-06-29
WO1991000733A1	1991-01-24

EP0138504A2	1985-04-24
US4659516A	1987-04-21
JP27495699A	1999-08-23
JP33833499A	1999-10-22

See also references of EP 1304334A4
CANCER RES., vol. 51, 1991, pages 3867
NATURE, vol. 375, 1995, pages 377 - 382

Shamoto, Ichio (New Ohtemachi Bldg. 2-1 Ohtemachi 2-chome Chiyoda-ku, Tokyo, JP)

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