Title:
NOVEL ANTIBACTERIAL PEPTIDE OR PEPTIDE ANALOG AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/206397
Kind Code:
A1
Abstract:
The present invention relates to a novel antibacterial peptide or peptide analog and a therapeutic use thereof for bacterial infection and, specifically, to a peptide or peptide analog having a structure in which an amphipathic, alpha-helical peptide composed of hydrophobic amino acids and hydrophilic amino acids is kinked, with a fatty acid coupled to the N-terminus thereof, and a therapeutic use thereof for bacterial infections, especially, infections by Gram-negative bacteria.
Inventors:
HYUN SOON-SIL (KR)
CHOI YOON-HWA (KR)
CHOO SEOL-AH (KR)
PARK TAE-WOO (KR)
YU JAE-HOON (KR)
CHOI YOON-HWA (KR)
CHOO SEOL-AH (KR)
PARK TAE-WOO (KR)
YU JAE-HOON (KR)
Application Number:
PCT/KR2021/004232
Publication Date:
October 14, 2021
Filing Date:
April 05, 2021
Export Citation:
Assignee:
CAMP THERAPEUTICS INC (KR)
International Classes:
A61K38/00; A61K38/08; A61P31/04
Foreign References:
| KR20170033790A | 2017-03-27 | |||
| US20190216939A1 | 2019-07-18 | |||
| KR20030061718A | 2003-07-22 | |||
| KR20180056226A | 2018-05-28 | |||
| KR101811437B1 | 2018-01-25 |
Other References:
CHOI YUNHWA: "Proline hinged amphipathic α-helical peptide enhances synergistic antimicrobial activity with various antibiotics by perturbing outer membrane of gram-negative bacteria.", MASTER'S THESIS, 1 December 2016 (2016-12-01), pages 1 - 45, XP055856625
Attorney, Agent or Firm:
JUNG, Yeo Soon (KR)
Download PDF: