NOVEL ANTICANCER FUSION PROTEIN AND USE THEREOF

WIPO Patent Application WO/2019/172614

A1

The present invention relates to a novel anticancer fusion protein and use thereof, and more specifically, provides a fusion protein in which a tumor necrosis factor (TNF) superfamily protein is joined to a self-assembled protein.

WO/2004/052276	COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER
JP2002535343	INDUSTRIAL APPLICABILITY: Stopping the lipophilic reaction of a virus inactivating agent
WO/2001/068873	NOVEL POLYPEPTIDE---A HUMAN LINKER ADHESION MOLECULE 12 AND POLYNUCLEOTIDE ENCODING IT

KIH MIN-WOO (KR)
LEE EUN JUNG (KR)
YANG YOO SOO (KR)
JEONG CHERL HYUN (KR)
KIM IN-SAN (KR)
KIM SOYOUN (KR)

PCT/KR2019/002531

September 12, 2019

March 05, 2019

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KOREA INST SCI & TECH (KR)
KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR)

C07K14/47; A61K9/50; A61K38/00; A61K45/06; A61K47/62; B82Y5/00

WO2011162492A2

2011-12-29

KR20170027683A	2017-03-10
KR20180008349A	2018-01-24

KACZMARCZYK, S. J. ET AL.: "Protein delivery using engineered virus-like particles", PNAS, vol. 108, 11 October 2011 (2011-10-11), pages 16998 - 17003, XP055072810, doi:10.1073/pnas.1101874108
FLAVO, E. ET AL.: "Antibody-drug conjugates: targeting melanoma with cisplatin encapsulated in protein-cage nanoparticles based on human ferritin", NANOSCALE, vol. 5, no. 24, 2013, pages 12278 - 12285, XP055195379, doi:10.1039/c3nr04268e
SIEGEMUND. M. ET AL.: "An optimized antibody-single-chain TRAIL fusion protein for cancer therapy", MABS, vol. 8, no. 5, 2016, pages 879 - 891, XP055630164, doi:10.1080/19420862.2016.1172163

HAN, Yun Ho (KR)

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