Title:
NOVEL ANTITHROMBOTIC AND ANTIATHEROSCLEROTIC AGENT AND METHOD FOR PRODUCING SAME (VARIANTS)
Document Type and Number:
WIPO Patent Application WO/2013/070116
Kind Code:
A3
Abstract:
The invention relates to the field of the chemical and pharmaceutical industry and medicine and concerns compounds which can be used to produce agents for the treatment of cardiovascular diseases. A novel compound of formula I is proposed which exhibits the properties of an exogenous nitric oxide donor and thus a thrombocyte aggregation inhibitor, as well as displaying antihypertensive activity and activating activity towards the enzyme soluble guanylyl cyclase. Variants of methods for synthesizing the above compound are also proposed.
Inventors:
GRANIK VLADIMIR GRIGORIEVICH (RU)
RYABOVA SVETLANA YUREVNA (RU)
PARSHIN VALERY ALEKSANDROVICH (RU)
ALEKSEEVA LUDMILA MIKHAYLOVNA (RU)
GRIGORIEV NIKITA BORISOVICH (RU)
RYABOVA SVETLANA YUREVNA (RU)
PARSHIN VALERY ALEKSANDROVICH (RU)
ALEKSEEVA LUDMILA MIKHAYLOVNA (RU)
GRIGORIEV NIKITA BORISOVICH (RU)
Application Number:
PCT/RU2012/000884
Publication Date:
July 18, 2013
Filing Date:
October 29, 2012
Export Citation:
Assignee:
PROTON OOO (RU)
International Classes:
C07D413/06; A61K31/422; A61P7/02; A61P9/00
Other References:
DATABASE REGISTRY [online] 4 June 2002 (2002-06-04), XP055122536, accession no. STN Database accession no. 425399-08-02
RYABOVA S JU. ET AL.: "Sintez i biologicheskaya aktivnost diendiaminoketonov indolinona-3 i pirrolin-2-ona-4.", KHIMIKO-FARMATSEVTICHESKY ZHURNAL, vol. 9, no. 29, 1995, pages 22 - 29, XP008169459
See also references of EP 2738167A4
RYABOVA S JU. ET AL.: "Sintez i biologicheskaya aktivnost diendiaminoketonov indolinona-3 i pirrolin-2-ona-4.", KHIMIKO-FARMATSEVTICHESKY ZHURNAL, vol. 9, no. 29, 1995, pages 22 - 29, XP008169459
See also references of EP 2738167A4
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