NOVEL ARYL DEUTERATED BENZYL ETHER SUBSTITUTED HETEROCYCLIC COMPOUND AS GLP1R AGONIST - MINDRANK THERAPEUTICS SUZHOU NEW DRUG RES AND DEVELOPMENT CO LTD

Title:

NOVEL ARYL DEUTERATED BENZYL ETHER SUBSTITUTED HETEROCYCLIC COMPOUND AS GLP1R AGONIST

Document Type and Number:

WIPO Patent Application WO/2024/051700

Kind Code:

A1

Abstract:

The present invention relates to a novel aryl ether substituted heterocyclic compound having GLP1R agonist activity. Specifically disclosed is a compound having a structure as represented by formula (I) as a GLP1R agonist, or a pharmaceutically acceptable salt, solvate, hydrate, isotopic substitute or isomer thereof.

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Inventors:

ZHANG LONG (CN)
NIU ZHANGMING (CN)

Application Number:

PCT/CN2023/117078

Publication Date:

March 14, 2024

Filing Date:

September 05, 2023

Export Citation:

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Assignee:

MINDRANK THERAPEUTICS SUZHOU NEW DRUG RES AND DEVELOPMENT CO LTD (CN)
MINDRANK AI LTD (CN)

International Classes:

C07D405/14; A61K31/4178; A61K31/4545; A61P3/10; A61P9/12; A61P19/02; A61P25/32; C07D401/14; C07D403/14; C07D407/14

Domestic Patent References:

WO2022165076A1	2022-08-04
WO2023049518A1	2023-03-30
WO2023029380A1	2023-03-09
WO2022235717A1	2022-11-10

Foreign References:

CN110325530A	2019-10-11
CN116675680A	2023-09-01
CN116102555A	2023-05-12

Attorney, Agent or Firm:

BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)

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