NOVEL BENZAMIDE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME

WIPO Patent Application WO/1995/018104

A1

A novel benzamide derivative represented by general formula (I), or a salt, hydrate or solvate thereof. The compound is useful as a 5-HT4 receptor agonist for preventing and treating central nervous system diseases such as schizophrenia, digestive tract movement disorders such as nausea, vomiting, irritable bowel syndrome, gastric ulcer and duodenal ulcer, heart action disorders such as cardiac failure, and urologic diseases such as urinary obstruction. It is also useful as an antinociceptive agent.

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SUZUKI TAKESHI (JP)
IMANISHI NAOKI (JP)
ITAHANA HIROTSUNE (JP)
KAMATO TAKESHI (JP)
MIYATA KEIJI (JP)
OHTA MITSUAKI (JP)

PCT/JP1994/002261

July 06, 1995

December 27, 1994

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YAMANOUCHI PHARMA CO LTD (JP)
SUZUKI TAKESHI (JP)
IMANISHI NAOKI (JP)
ITAHANA HIROTSUNE (JP)
KAMATO TAKESHI (JP)
MIYATA KEIJI (JP)
OHTA MITSUAKI (JP)

C07D207/09; C07D211/26; C07D223/04; C07D241/04; C07D241/08; C07D243/08; C07D265/30; C07D267/10; C07D279/12; C07D281/06; C07D453/02; C07D487/08; (IPC1-7): C07D207/09; A61K31/40; A61K31/445; C07D211/12; C07D211/14; C07D223/04; C07D241/04; C07D241/08; C07D243/08; C07D265/30; C07D267/10; C07D279/12; C07D281/06; C07D453/02; C07D487/08; A61K31/495; A61K31/535; A61K31/54; A61K31/55

JPH06306075A	1994-11-01
JPH05507942A	1993-11-11

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