Title:
NOVEL BENZAZEPINE SPIRO DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2022/111581
Kind Code:
A1
Abstract:
A benzazepine spiro derivative as represented by formula (I) and a pharmaceutically acceptable salt thereof, and the use of a compound in the diagnosis, prevention and/or treatment of diseases related to vasopressin receptors.
Inventors:
LU HONGFU (CN)
LV YONGCONG (CN)
YE YAN (CN)
PENG JIANBIAO (CN)
GUO HAIBING (CN)
LV YONGCONG (CN)
YE YAN (CN)
PENG JIANBIAO (CN)
GUO HAIBING (CN)
Application Number:
PCT/CN2021/133158
Publication Date:
June 02, 2022
Filing Date:
November 25, 2021
Export Citation:
Assignee:
SHANGHAI JEMINCARE PHARMACEUTICAL CO LTD (CN)
JIANGXI JEMINCARE GROUP CO LTD (CN)
JIANGXI JEMINCARE GROUP CO LTD (CN)
International Classes:
C07D223/16; A61K31/55; A61P1/16; A61P5/38; A61P9/04; A61P9/12; A61P13/12; A61P15/06; A61P25/24; C07D405/02; C07D487/10
Foreign References:
| CN1449386A | 2003-10-15 | |||
| CN101541806A | 2009-09-23 | |||
| CN102796077A | 2012-11-28 | |||
| CN1127508A | 1996-07-24 | |||
| CN202011353057A | 2020-11-26 | |||
| CN202111322711A | 2021-11-09 |
Other References:
XIANG, M. A. ET AL.: "Synthesis and evaluation of nonpeptide substituted spirobenzazepines as potent vasopressin antagonists", BIOORG. MED. CHEM. LETT., vol. 14, no. 12, 14 June 2004 (2004-06-14), XP004841361, DOI: 10.1016/j.bmcl.2004.04.016
TAMIO YAMAGUCHI ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, 2004
TAMIO YAMAGUCHI ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, 2004
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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