Title:
NOVEL BENZODIAZEPINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/1992/011246
Kind Code:
A1
Abstract:
A novel benzodiazepine derivative represented by general formula (I), a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof, and a process for producing the same. In formula (I), R?1¿ represents optionally substituted aryl, five-membered monocyclic group, six-membered monocyclic group or aromatic heterocyclic group comprising five-membered and six-membered rings; and R?2¿ represents optionally substituted aryl. The compound (I) has a CCK-B receptor antagonism and an action of inhibiting pentagastrin-stimulated gastric secretion and hence is useful in treating and preventing the diseases wherein a CCK-B receptor and a gastrin receptor participate.
Inventors:
SATOH MASATO (JP)
KONDOH YUTAKA (JP)
OKAMOTO YOSHINORI (JP)
NISHIDA AKITO (JP)
HONDA KAZUO (JP)
SAITO MASAYUKI (JP)
KONDOH YUTAKA (JP)
OKAMOTO YOSHINORI (JP)
NISHIDA AKITO (JP)
HONDA KAZUO (JP)
SAITO MASAYUKI (JP)
Application Number:
PCT/JP1991/001720
Publication Date:
July 09, 1992
Filing Date:
December 17, 1991
Export Citation:
Assignee:
YAMANOUCHI PHARMA CO LTD (JP)
International Classes:
A61K31/55; B65D25/52; B65D83/08; B65H35/10; C07D243/24; C07D243/26; C07D401/06; C07D403/04; C07D403/06; C07D409/06; (IPC1-7): A61K31/55; C07D243/24; C07D243/26
Foreign References:
| EP0284256A1 | 1988-09-28 | |||
| JPS6178773A | 1986-04-22 | |||
| JPS54157585A | 1979-12-12 |
Other References:
See also references of EP 0591529A4
Attorney, Agent or Firm:
Nagai, Shozo (Patent Department, 1-8, Azusawa 1-chom, Itabashi-ku Tokyo 174, JP)
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