Title:
NOVEL BENZODIAZEPINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/1994/000438
Kind Code:
A1
Abstract:
A novel benzodiazepine derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof. These compounds are useful as medicines, in particular, for treating and preventing diseases in which CCK-B receptor and gastrin receptor participate, because they have CCK-B receptor antagonism, gastrin receptor antagonism and the effect of inhibiting gastric juice secretion.
Inventors:
SATOH MASATO (JP)
OKAMOTO YOSHINORI (JP)
KOSHIO HIROYUKI (JP)
NISHIDA AKITO (JP)
MIYATA KEIJI (JP)
OHTA MITSUAKI (JP)
RYDER HAMISH (GB)
KENDRICK DAVID A (GB)
SEMPLE GRAEME (GB)
SZELKE MICHAEL (GB)
OKAMOTO YOSHINORI (JP)
KOSHIO HIROYUKI (JP)
NISHIDA AKITO (JP)
MIYATA KEIJI (JP)
OHTA MITSUAKI (JP)
RYDER HAMISH (GB)
KENDRICK DAVID A (GB)
SEMPLE GRAEME (GB)
SZELKE MICHAEL (GB)
Application Number:
PCT/JP1993/000844
Publication Date:
January 06, 1994
Filing Date:
June 22, 1993
Export Citation:
Assignee:
YAMANOUCHI PHARMA CO LTD (JP)
FERRING BV (NL)
SATOH MASATO (JP)
OKAMOTO YOSHINORI (JP)
KOSHIO HIROYUKI (JP)
NISHIDA AKITO (JP)
MIYATA KEIJI (JP)
OHTA MITSUAKI (JP)
RYDER HAMISH (GB)
KENDRICK DAVID A (GB)
SEMPLE GRAEME (GB)
SZELKE MICHAEL (GB)
FERRING BV (NL)
SATOH MASATO (JP)
OKAMOTO YOSHINORI (JP)
KOSHIO HIROYUKI (JP)
NISHIDA AKITO (JP)
MIYATA KEIJI (JP)
OHTA MITSUAKI (JP)
RYDER HAMISH (GB)
KENDRICK DAVID A (GB)
SEMPLE GRAEME (GB)
SZELKE MICHAEL (GB)
International Classes:
C07D243/24; C07D401/04; C07D401/12; C07D403/12; (IPC1-7): C07D243/24; A61K31/55
Foreign References:
| JPS6163666A | 1986-04-01 | |||
| JPS61148181A | 1986-07-05 | |||
| JPH02142795A | 1990-05-31 | |||
| JPH02275884A | 1990-11-09 |
Other References:
"Nature", 312, page 363 (1984).
See also references of EP 0647632A4
See also references of EP 0647632A4
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