Title:
NOVEL BETA-CAROTENE 15,15-OXYGENASE VARIANT AND RETINOID PRODUCTION METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2023/287256
Kind Code:
A1
Abstract:
The present application pertains to a novel beta-carotene 15,15'-oxygenase variant, a microorganism including the variant, a method for production of retinoid, using the microorganism, a composition for production of retinoid, and a use of the variant or microorganism for producing retinoid.
Inventors:
PARK HYE MIN (KR)
LEE PETER (KR)
LEE DONG PIL (KR)
KIM JAE EUNG (KR)
LEE PETER (KR)
LEE DONG PIL (KR)
KIM JAE EUNG (KR)
Application Number:
PCT/KR2022/010385
Publication Date:
January 19, 2023
Filing Date:
July 15, 2022
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N9/02; C12N15/52; C12N15/80; C12P23/00
Domestic Patent References:
| WO2021009194A1 | 2021-01-21 |
Foreign References:
| US20200231993A1 | 2020-07-23 | |||
| KR20200066752A | 2020-06-11 | |||
| US20200277644A1 | 2020-09-03 | |||
| KR20200136813A | 2020-12-08 | |||
| US7662943B2 | 2010-02-16 | |||
| US10584338B2 | 2020-03-10 | |||
| US10273491B2 | 2019-04-30 |
Other References:
DATABASE GenBank NCBI; .. . : "Beta-carotene 15,15`-dioxygenase ", XP093023502
YEONG-SU KIM ; CHANG-SU PARK ; DEOK-KUN OH: "Retinal production from β-carotene by β-carotene 15,15′-dioxygenase from an unculturable marine bacterium", BIOTECHNOLOGY LETTERS, SPRINGER NETHERLANDS, DORDRECHT, vol. 32, no. 7, 13 March 2010 (2010-03-13), Dordrecht , pages 957 - 961, XP019813421, ISSN: 1573-6776
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "Trends Genet.", vol. 16, 2000, article "EMBOSS: The European Molecular Biology Open Software Suite", pages: 276 - 277
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
RICE ET AL., EMBOSS: THE EUROPEAN MOLECULAR BIOLOGY OPEN SOFTWARE SUITE, 2000
TRENDS GENET., vol. 16, pages 276 - 277
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
SITNICKA ET AL.: "Functional Analysis of Genes.", ADVANCES IN CELL BIOLOGY., vol. 7-8, no. 1-16, 2010, pages 50 - 51
SAMBROOK ET AL., MOLECULAR CLONING, 2012
JANG ET AL., MICROBIAL CELL FACTORIES, vol. 10, no. 59, 2011
CHOI ET AL., ANTIOXIDANTS, 2020
D.-C. CHEN ET AL., APPL MICROBIOL BIOTECHNOL, 1997
YEONG-SU KIM ; CHANG-SU PARK ; DEOK-KUN OH: "Retinal production from β-carotene by β-carotene 15,15′-dioxygenase from an unculturable marine bacterium", BIOTECHNOLOGY LETTERS, SPRINGER NETHERLANDS, DORDRECHT, vol. 32, no. 7, 13 March 2010 (2010-03-13), Dordrecht , pages 957 - 961, XP019813421, ISSN: 1573-6776
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "Trends Genet.", vol. 16, 2000, article "EMBOSS: The European Molecular Biology Open Software Suite", pages: 276 - 277
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
RICE ET AL., EMBOSS: THE EUROPEAN MOLECULAR BIOLOGY OPEN SOFTWARE SUITE, 2000
TRENDS GENET., vol. 16, pages 276 - 277
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
SITNICKA ET AL.: "Functional Analysis of Genes.", ADVANCES IN CELL BIOLOGY., vol. 7-8, no. 1-16, 2010, pages 50 - 51
SAMBROOK ET AL., MOLECULAR CLONING, 2012
JANG ET AL., MICROBIAL CELL FACTORIES, vol. 10, no. 59, 2011
CHOI ET AL., ANTIOXIDANTS, 2020
D.-C. CHEN ET AL., APPL MICROBIOL BIOTECHNOL, 1997
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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