Title:
NOVEL BICYCLIC UREA DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS
Document Type and Number:
WIPO Patent Application WO2004078748
Kind Code:
A3
Abstract:
This invention relates to novel diary) ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
Inventors:
DUMAS JACQUES (US)
BOYER STEPHEN (DE)
VERMA SHARAD (US)
ADNANE LILA (US)
CHEN YUANWEI (US)
LEE WENDY (US)
PHILLIPS BARTON (US)
SMITH ROGER A (US)
SCOTT WILLIAM J (US)
BURKE JENNIFER (US)
CHEN JIANQING (US)
CHEN ZHI (US)
FAN JIANMEI (US)
MIRANDA KARL (US)
RAUDENBUSH BRIAN (US)
REDMAN ANIKO (US)
SHAO JIANXING (US)
SU NING (US)
WANG GAN (US)
YI LIN (US)
ZHU QINGMING (US)
BOYER STEPHEN (DE)
VERMA SHARAD (US)
ADNANE LILA (US)
CHEN YUANWEI (US)
LEE WENDY (US)
PHILLIPS BARTON (US)
SMITH ROGER A (US)
SCOTT WILLIAM J (US)
BURKE JENNIFER (US)
CHEN JIANQING (US)
CHEN ZHI (US)
FAN JIANMEI (US)
MIRANDA KARL (US)
RAUDENBUSH BRIAN (US)
REDMAN ANIKO (US)
SHAO JIANXING (US)
SU NING (US)
WANG GAN (US)
YI LIN (US)
ZHU QINGMING (US)
Application Number:
PCT/US2004/006287
Publication Date:
November 11, 2004
Filing Date:
March 01, 2004
Export Citation:
Assignee:
BAYER PHARMACEUTICALS CORP (US)
DUMAS JACQUES (US)
BOYER STEPHEN (DE)
VERMA SHARAD (US)
ADNANE LILA (US)
CHEN YUANWEI (US)
LEE WENDY (US)
PHILLIPS BARTON (US)
SMITH ROGER A (US)
SCOTT WILLIAM J (US)
BURKE JENNIFER (US)
CHEN JIANQING (US)
CHEN ZHI (US)
FAN JIANMEI (US)
MIRANDA KARL (US)
RAUDENBUSH BRIAN (US)
REDMAN ANIKO (US)
SHAO JIANXING (US)
SU NING (US)
WANG GAN (US)
YI LIN (US)
ZHU QINGMING (US)
DUMAS JACQUES (US)
BOYER STEPHEN (DE)
VERMA SHARAD (US)
ADNANE LILA (US)
CHEN YUANWEI (US)
LEE WENDY (US)
PHILLIPS BARTON (US)
SMITH ROGER A (US)
SCOTT WILLIAM J (US)
BURKE JENNIFER (US)
CHEN JIANQING (US)
CHEN ZHI (US)
FAN JIANMEI (US)
MIRANDA KARL (US)
RAUDENBUSH BRIAN (US)
REDMAN ANIKO (US)
SHAO JIANXING (US)
SU NING (US)
WANG GAN (US)
YI LIN (US)
ZHU QINGMING (US)
International Classes:
A61K31/443; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61P35/00; C07D213/89; C07D401/12; C07D401/14; C07D405/12; C07D405/14; C07D409/12; C07D413/12; C07D417/12; (IPC1-7): C07D401/12; C07D417/12; C07D413/12; C07D213/89; C07D405/12; C07D409/12; C07D405/14; C07D401/14; A61K31/443; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61P35/00
Domestic Patent References:
| WO2002062763A2 | 2002-08-15 | |||
| WO2003068228A1 | 2003-08-21 | |||
| WO2000042012A1 | 2000-07-20 | |||
| WO1999032106A1 | 1999-07-01 | |||
| WO2001036403A1 | 2001-05-25 | |||
| WO1999024035A1 | 1999-05-20 |
Other References:
DUMAS J: "PROTEIN KINASE INHIBITORS FROM THE UREA CLASS", CURRENT OPINION IN DRUG DISCOVERY AND DEVELOPMENT, CURRENT DRUGS, LONDON, GB, vol. 5, no. 5, 2002, pages 718 - 727, XP009011493, ISSN: 1367-6733
HOTTE S J ET AL: "BAY 43-9006: EARLY CLINICAL DATA IN PATIENTS WITH ADVANCED SOLID MALIGNANCIES", CURRENT PHARMACEUTICAL DESIGN, BENTHAM SCIENCE PUBLISHERS, SCHIPHOL, NL, vol. 8, no. 25, 2002, pages 2249 - 2253, XP001145745, ISSN: 1381-6128
HOTTE S J ET AL: "BAY 43-9006: EARLY CLINICAL DATA IN PATIENTS WITH ADVANCED SOLID MALIGNANCIES", CURRENT PHARMACEUTICAL DESIGN, BENTHAM SCIENCE PUBLISHERS, SCHIPHOL, NL, vol. 8, no. 25, 2002, pages 2249 - 2253, XP001145745, ISSN: 1381-6128
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