NOVEL BIOLOGICAL ACTIVITY TESTING STRUCTURE FOR TRACKING SINGLE CELL, USING GELLING AGENTS

Title:

NOVEL BIOLOGICAL ACTIVITY TESTING STRUCTURE FOR TRACKING SINGLE CELL, USING GELLING AGENTS

Document Type and Number:

WIPO Patent Application WO/2016/060301

Kind Code:

A1

Abstract:

The present invention relates to: a novel biological activity testing structure for tracking a single cell, using gelling agents; and a biological activity testing system comprising the same. In addition, the present invention relates to a method for testing biological activity, testing drug susceptibility, screening for antibiotics and diagnosis, using the testing structure. The biological activity testing structure, provided by the present invention, can very quickly and simply carry out a drug susceptibility test, drug screening and diagnosis for bacteria, particularly Mycobacterium tuberculosis. Particularly, DST and diagnosis are enabled irrespective of inoculation effects, or only by pretreatment without a step of concentrating human sputum, and thus a test can be outstandingly quickly and accurately, and simply carried out compared with a conventionally developed tuberculosis diagnostic or DST system. In addition, the structure according to the present invention allows tuberculosis diagnosis and a drug susceptibility test to be carried out simultaneously, and thus a technique provided by the present invention can effectively replace a conventional technique.

Inventors:

JUNG YONG-GYUN (KR)
KIM EUN GEUN (KR)
YOO JUNG HEON (KR)
PARK KYUNG-OCK (KR)
KWON SUNGHOON (KR)
CHOI JUNGIL (KR)
KIM HEE JIN (KR)
RYOO SUNG WEON (KR)
KIM HAEUN (KR)
JEOUNG HYEON JU (KR)
LEE EUN HEE (KR)
KIM HYEJIN (KR)

Application Number:

PCT/KR2014/009755

Publication Date:

April 21, 2016

Filing Date:

October 16, 2014

Export Citation:

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Assignee:

QUANTA MATRIX CO LTD (KR)
SNU R&DB FOUNDATION (KR)
KOREAN NAT TUBERCULOSIS ASS (KR)

International Classes:

C12M1/18; C12Q1/02

Foreign References:

KR20130089619A	2013-08-12
KR101446526B1	2014-10-08
KR20070033685A	2007-03-27
JP2009513160A	2009-04-02

Other References: